The invention relates to an arrangement (1) for non-invasively characterising cerebrospinal fluid and other bodily fluids, • comprising a sensor head (7) for emitting terahertz radiation (T) and receiving its reflections (R), which sensor head, during use, is applied to the patient (3) in such a way that the terahertz radiation (T) radiates into the bodily fluid, • comprising an electronic evaluation circuit for calculating measurement data from the emitted and received radiation (T, R), wherein this circuit automatically determines the extinction of different wavelengths and, from this, calculates the concentration of different substances in the bodily fluid, • and comprising a display (8) for optically representing the data calculated by the evaluation circuit as results.

• 출원번호 : EP2024/071758
• 출원인 : LALA, Helin;LALA, Sultan;
• 특허번호 :
• IPC : G01N-021/3581(2014.01);A61B-005/00(2006.01);A61B-005/0507(2021.01);A61B-005/145(2006.01);

Present invention discloses a novel method for cervical cancer patients undergoing brachytherapy which combines a rectal retractor (RR) blade with radio-opaque vaginal packing (VP) to displace the rectum and bladder away from radiation sources in High-dose-rate (HDR) intracavity brachytherapy (ICB). While doing conventional brachytherapy with T&R applicators, the inventors deliberately placed radio-opaque vaginal packing (VP), posterior and cranial to the rectal retractor (RR) blade, to retract the rectum away from the radiation sources. The combination procedure Rectal retractor (RR) and Radio-opaque vaginal opaque (VP) is less time consuming and leads to significant reduction in dose to ICRU rectal points to 13.03% and reduction in rectal dose per fraction is 15% (p = 0.013).

• 출원번호 : IN2024/051420
• 출원인 : VATS, Dr. Siddharth;-, Dr Shabnum;GUPTA, Dr Manish;CHANDRAKANT, Dr Lalit;
• 특허번호 :
• IPC : A61N-005/00(2006.01);A61B-017/02(2006.01);

The present invention inter alia relates to a chimeric human CD8 Co-receptor, wherein the CD8 Co-receptor comprises a polypeptide including at least one functional polypeptide domain or a functional polypeptide motif of a wildtype human CD8α Co- receptor, and wherein said polypeptide further comprises at least one CD8β-derived polypeptide region including a functional polypeptide domain or a functional polypeptide motif of a wildtype human CD8β Co-receptor.The present invention also relates to a nucleic acid encoding the chimeric CD8 Co-receptor, a vector comprising the nuclear acid encoding for the chimeric human CD8 Co-receptor, as well as to isolated T-cells being transduced with the nucleic acid or the with the vector, and to isolated T-cells being transduced to express the chimeric CD8 Co-receptor. The invention further relates to a kit for preparing the isolated T-cells of the present invention, as well as to a pharmaceutical composition comprising the T-cells. The invention also relates to a method for preparing a T-cell for immunotherapy, and to a method for treating a patient having cancer comprising administering the pharmaceutical composition.

• 출원번호 : EP2024/071706
• 출원인 : T-KNIFE GMBH
• 특허번호 :
• IPC : A61K-039/00(2006.01);A61P-035/00(2006.01);C07K-014/705(2006.01);

The present invention relates to an apparatus (100) and a process for treating activated and/or contaminated components (90). In particular, the apparatus (100) comprises a container (10) comprising an internal volume (V). The container (10) is provided with a closure element (20) which is movable between an operating opening configuration of the container (10) and an operating closing configuration thereof. The apparatus (100) further comprises an inflatable joint (50), configured to operate in association with said closure element (20) so as to achieve a watertight sealing of the container (10) when said container is in the operating closing configuration. The apparatus (100) further comprises a cutting device (40) arranged inside the internal volume (V) of said container (10), at least one effluent treatment device (60) and at least one fluid suction device (70) communicating with the internal volume (V) of said container (10) and with said treatment device (60) of an effluent.

• 출원번호 : IB2024/057417
• 출원인 : GREEN-LAND SRL
• 특허번호 :
• IPC : G21F-009/34(2006.01);B01D-021/00(2006.01);G21F-009/36(2006.01);

The present invention inter alia relates to an enhanced chimeric CD8 Co-receptor, wherein the CD8 Co-receptor comprises a polypeptide including at least one functional polypeptide domain or a functional polypeptide motif of a CD8 Co-receptor, and wherein said polypeptide further comprises at least one CD8-derived polypeptide region including a functional polypeptide domain or a functional polypeptide motif of a wildtype human CD8 Co-receptor.The enhanced chimeric CD8 Co-receptor further comprises at least one cytoplasmic polypeptide domain or cytoplasmic polypeptide motif of a tumor necrosis factor receptor superfamily protein, a immunoglobulin superfamily (IgSF) protein, and/or an ITAM-associated receptor. The present invention also relates to a nucleic acid encoding the enhanced chimeric CD8 Co-receptor, a vector comprising the nuclear acid encoding for the enhanced chimeric human CD8 Co-receptor, as well as to isolated T-cells being transduced, transformed or transfected with the nucleic acid or the with the vector, and to isolated T-cells being transduced, transformed or transfected to express the enhanced chimeric CD8 Co-receptor as well as to engineered T-cells expressing the chimeric CD8 Co-receptor. The invention further relates to a kit for preparing the isolated T-cells of the present invention, as well as to a pharmaceutical composition comprising the T-cells. The invention also relates to a method for preparing a T-cell for immunotherapy, and to a method for treating a patient having a disease comprising administering the pharmaceutical composition.

• 출원번호 : EP2024/071709
• 출원인 : T-KNIFE GMBH
• 특허번호 :
• IPC : C07K-014/73(2006.01);C07K-014/705(2006.01);A61K-038/00(2006.01);

Provided is an integrated circuit capable of maintaining high reliability even under a severe environment such as a high radiation environment.　An integrated circuit 1 comprises: a master latch 3 for receiving an input of an input signal, and outputting a signal at a timing based on a master clock signal; and N (N is an odd number of 3 or more) slave latches 4 for receiving an input of the signal outputted from the master latch 3, and outputting an output signal at a timing based on a slave clock signal. The master latch 3 outputs, to the slave latches 4, a signal of a value determined on the basis of the input signal and the input of the outputted signal. Each of the slave latches 4 is configured to output an output signal of a value determined on the basis of a majority decision result of signals respectively outputted from the N slave latches 4 or a majority decision result of signals, which the slave latches 4 have respectively received, as inputs, from the master latch 3.

• 출원번호 : JP2024/027345
• 출원인 : NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY
• 특허번호 :
• IPC : H03K-003/037(2006.01);H03K-019/23(2006.01);H03K-019/096(2006.01);

An object of the present invention is to provide a composite oxide particle material formed of zinc molybdate having a high purity and a high circularity. The composite oxide particle material is formed of a composite oxide, of molybdenum and zinc, having an average particle diameter of 0.1 μm or more and 5.0 μm or less, a BET specific surface area of 1 m2/g or more and 20 m2/g or less, (peak intensity at 26.6° according to XRD)/(peak intensity at 24.2°) of 1.20 or more, an impurity concentration of 1 mass % or less, and a circularity of 0.90 or more. XRD is measured with CuKα radiation.

• 출원번호 : 18790034
• 출원인 : ADMATECHS CO., LTD.
• 특허번호 :
• IPC : C08K-009/06(2006.01);C01G-039/00(2006.01);C09C-001/00(2006.01);C09C-003/12(2006.01);

There are provided: a compression plate for a medical imaging apparatus, which is used in a medical imaging apparatus including a radiation generation unit, a radiation detection unit, an ultrasound probe, and an imaging table disposed between the radiation generation unit and the radiation detection unit and which is used for compressing a subject by sandwiching the subject between the imaging table and the compression plate, the compression plate for a medical imaging apparatus including a polymethylpentene resin-containing material having a bending elastic modulus of 1 GPa or more and a thermal deformation temperature of 100° C. or higher, in which the polymethylpentene resin-containing material contains a polymethylpentene compound containing 1 to 300 ppm of a sulfur element based on mass; a polymethylpentene resin-containing material that is suitably used for the compression plate; and a medical imaging apparatus having the compression plate.

• 출원번호 : 18790634
• 출원인 : FUJIFILM Corporation
• 특허번호 :
• IPC : A61B-006/04(2006.01);A61B-006/00(2006.01);A61B-006/50(2006.01);A61B-008/00(2006.01);A61B-008/08(2006.01);

The device comprises at least a laser source (5); an optical fiber (1) with an optical radiation entrance end (1.2) and an optical radiation output end (1.1); and a coupling system (8) for coupling the laser source (5) and the optical fiber (1), adapted to inject an optical radiation emitted by the laser source (5) into the entrance end (1.2) of the optical fiber (1). The optical fiber (1) is a multi-mode optical fiber. The coupling system (8) is adapted to inject the optical radiation into the optical fiber (1) with such an inclination (a) as to reduce or eliminate the fundamental transmission mode and to promote the transmission according to at least one higher-order transmission mode The optical radiation at the output end (1.1) of the optical fiber (1) has a cone-shaped distribution (3) wherein the intensity is maximal on the peripheral volume of an emission cone and is minimal inside the emission cone.

• 출원번호 : 18790316
• 출원인 : MASOTTI, Leonardo
• 특허번호 :
• IPC : A61B-018/24(2006.01);A61B-018/00(2006.01);A61B-018/20(2006.01);A61B-018/22(2006.01);

Embodiments disclosed herein show a novel helical meandered antenna, wherein some embodiments feature tunability through the application of DC voltage to switch and connect multiple antenna arms. The design, successfully fabricated and tested for wireless applications, exhibits a compact size and omnidirectional radiation pattern. The use of diodes as effective components for tunability is explored, allowing adjustments in the operating frequency of the helix. Extensive simulations and measurements were conducted on over 15 different antenna designs, showing consistent results. The proposed helical antenna demonstrates a fine-tunable operation frequency change from 459 MHz to 338 MHz (over 30% change) with low voltage supplied DC from 0 V to 1.5 V.

• 출원번호 : 18791182
• 출원인 : The Trustees of the California State University
• 특허번호 :
• IPC : H01Q-011/08(2006.01);H04B-017/00(2006.01);