Bone marrow, the primary hematopoietic organ, is more sensitive than other organs when exposed to ionizing radiation or chemotherapeutic drugs due to the fragile hematopoietic stem and progenitor cells (HSPCs). Described herein are novel compounds, compositions, and methods comprising protective drug-based conjugates to achieve the specific protection of HSPCs in the bone marrow.

• 출원번호 : US2024/038573
• 출원인 : ZYMERON CORPORATION
• 특허번호 :
• IPC : A61K-047/54(2017.01);A61K-047/65(2017.01);A61P-019/08(2006.01);A61P-039/00(2006.01);

The invention relates to devices for the radiation detection and analysis, in particular to portable alpha particle sensors adapted for the identification and quantification of radioactive decay products - particles. The proposed invention is a battery-powered pulse ionization chamber particle sensor comprising at least one electric battery, at least one switch S, a voltage converter DC/DC, a capacitor C, a processor MCU, a current pulse amplifier A, an ionization chamber K with an electrode of zero potential placed therein. The ionization chamber K is designed with the possibility of placing a source of particles in it. Furthermore at least one electric battery is electrically connected to the voltage converter DC/DC by means of a switch S, the operation of which is controllable by the processor MCU. The voltage converter DC/DC is electrically connected to the capacitor C and the ionization chamber K. The electrode of the ionization chamber K is electrically connected to the processor MCU through the current pulse amplifier A. The processor MCU furthermore is adapted to execute the instructions: (i) count electrical pulses N, which coming from the K electrode of the ionization chamber and which are amplified by the amplifier A; (ii) by means of at least one switch S, controllably periodically electrically connect the supply of electric energy from at least one electric battery to the voltage converter DC/DC and further in the circuit; (iii) determine the voltage value on the capacitor C and, upon reaching the previously set maximum value of the voltage, by means of the switch S, electrically disconnect the supply of electric energy from the electric battery to the voltage converter DC/DC and further in the circuit.

• 출원번호 : LV2024/050009
• 출원인 : SAF TEHNIKA, AS
• 특허번호 :
• IPC : G01T-001/17(2006.01);G01T-001/185(2006.01);

The present invention relates to a laminated pane assembly (100) having a sensor window (4), at least comprising: • a sensor holding device (5), which is attached to a second surface (IV) of the inner pane (2) and in which at least one sensor of a vehicle driving assistance system is arranged, • at least one optically transparent sensor window (2) of the laminated pane (10), through which the beam path of the sensor (3) passes, • a heating device (6), wherein the heating device (6) has at least one radiation source (7) in the infrared wavelength range and is arranged on the sensor holding device (5), and wherein the radiation source (7) is arranged in a recess in the sensor holding device (5).

• 출원번호 : EP2024/070417
• 출원인 : SAINT-GOBAIN GLASS FRANCE
• 특허번호 :
• IPC : B32B-017/10(2006.01);B32B-003/08(2006.01);

The present invention relates to a 3D printing filament for medical imaging educational human equivalent bones with radiopaque that is most similar to human bones, which allows stable and radiation-free computed tomography (CT) medical imaging examination and education using the computed tomography (CT) for medical images by mixing and drying barium sulfate with thermoplastic resin to obtain chips, melt-extruding, cooling and winding the obtained chips to create a filament, and manufacturing human equivalent bones through 3D printing of the wound filament.

• 출원번호 : 24189372.6
• 출원인 : Petela Co. Ltd.
• 특허번호 :
• IPC : B29C-064/118(2017.01);B33Y-010/00(2015.01);B33Y-070/10(2020.01);B33Y-080/00(2015.01);G09B-023/28(2006.01);

PROBLEM TO BE SOLVED: To provide a radiation-sensitive resin composition that can exhibit sensitivity, CDU performance, and resolution at sufficient levels when applied to next-generation technology, and a method for forming patterns.SOLUTION: A radiation-sensitive resin composition includes a resin containing a structural unit A represented by formula (1), a radiation-sensitive sulfonic acid generator with a specific structure, and a solvent.SELECTED DRAWING: None

• 출원번호 : 2024114875
• 출원인 : JSR CORP
• 특허번호 :
• IPC : G03F-007/039(2006.01);G03F-007/004(2006.01);C08F-220/16(2006.01);C08F-212/14(2006.01);C07D-333/76(2006.01);C07D-335/16(2006.01);C07D-327/04(2006.01);C07D-317/72(2006.01);G03F-007/20(2006.01);C07C-381/12(2006.01);C07C-309/17(2006.01);C07C-309/12(2006.01);C07C-309/31(2006.01);C07C-309/19(2006.01);C07C-309/07(2006.01);

The present inventors identified many nuclear proteins contained in the extract of skin tissue by mass spectrometry, randomly selected multiple partial amino acid sequences of the nuclear proteins, chemically synthesized peptides consisting of the partial amino acid sequences, and examined their activity of mobilizing mesenchymal stem cells. As a result, it was found that these multiple peptides show the activity of mobilizing mesenchymal stem cells into peripheral blood, even though their amino acid sequences are completely different from each other. The inventors also found that fragment peptides of the nuclear proteins have therapeutic effects on diseases characterized by inflammation and abnormalities of the immune system (e.g., inflammatory bowel disease and psoriasis). Based on these findings, a new regenerative medicine technology that can overcome the problems of cell transplantation therapy is provided.

• 출원번호 : 18776908
• 출원인 : TAMAI, Katsuto
• 특허번호 :
• IPC : C07K-014/47(2006.01);A61K-038/00(2006.01);A61P-001/00(2006.01);A61P-017/06(2006.01);A61P-037/06(2006.01);

The present disclosure, in an embodiment, is a facility that includes a device configured to generate a beam having an energy range of 5 MeV to 500 MeV, a first radiation shielding wall surrounding the device, a second radiation shielding wall surrounding the first radiation shielding wall, radiation shielding fill material positioned between the first radiation shielding wall and the second radiation shielding wall forming a first barrier. In embodiments, the radiation shielding fill material includes at least fifty percent by weight of an element having an atomic number from 12 to 83, and a thickness of the first barrier is 0.5 meter to 6 meters.

• 출원번호 : 18777521
• 출원인 : Rad Technology Medical Systems LLC
• 특허번호 :
• IPC : G21F-007/00(2006.01);G21F-001/08(2006.01);G21F-003/00(2006.01);

Crosslinking aromatic compounds are described which have structure (I). Also described, are compositions including these crosslinking compounds, for instance ones which also comprising a photoacid generator. Also, described are methods of using such compositions to coat a substrate and by exposing it to radiation producing an image which may be used as a mask in the manufacture of microelectronics. Also disclosed is a selective iodination method for multiphenolic compounds at the ortho position to the phenol functionality, employing a 1-iodopyrrolidine-2,5-dione moiety in the presence of an arylsulfonic acid which produces the phenolic precursors of crosslinking aromatic compounds with selective iodination.

• 출원번호 : EP2024/070384
• 출원인 : MERCK PATENT GMBH
• 특허번호 :
• IPC :

A system for optical communications, comprising: a pulse generator (1) configured to generate a train of pulses of electromagnetic radiation; a modulator (2) optically connected to the pulse generator (1) and configured to modulate the train via modulating an amplitude of at least some of the pulses of the train such that the modulated train comprises a first set of pulses and a second set of pulses, wherein the amplitude of the pulses of the first set is smaller than the amplitude of the pulses of the second set; a saturable noise suppressor (3) which is optically connected to the modulator (2), comprises a saturable absorber (4), and is configured to receive the modulated train, attenuate the amplitude of the pulses of the first set, and output the pulses of the second set and the attenuated pulses of the first set. Also, a method for optical communications, and a use of the system.

• 출원번호 : EP2024/070457
• 출원인 : FYLA LASER, S.L.
• 특허번호 :
• IPC : H04B-010/11(2013.01);H04B-010/54(2013.01);

A method for generating electron density maps of a region of interest of a subject for adaptive radiation therapy using a magnetic resonance (MR) linear accelerator (Linac) radiation treatment system includes receiving a radiation treatment plan associated with the region of interest of the subject, acquiring a plurality of projections using one or more X-ray beams from a linear accelerator and a flat panel detector of the MR-Linac system, reconstructing one or more projection images based on the one or more projections, generating one or more electron density maps based on the one or more projection images, and generating an updated radiation treatment plan associated with the region of interest of the subject based on the one or more electron density maps.

• 출원번호 : US2024/038506
• 출원인 : THE BRIGHAM AND WOMEN' S HOSPITAL, INC.
• 특허번호 :
• IPC : A61B-005/055(2006.01);G16H-030/00(2018.01);