An intelligent anesthetization system for transperineal prostate puncturing based on multimodal medical images is provided. The system includes a coordinate system definition module, a markup of MRI sequence image and 3D reconstruction module, an ultrasonic data extraction module, a registration module and an anesthetic planning module. This system transforms images in the preoperative nuclear magnetic imaging coordinate system as well as the target area of anesthetization into real-time electromagnetic emitter coordinate system through multimodal medical image registration, thereby realizing the comprehensive fusion of the target area of anesthetization in nuclear magnetic resonance image and ultrasonic image, which can be used for medical teaching or surgical guidance and can help to achieve precise positioning of anesthetized area for transperineal prostate biopsy.

• 출원번호 : 18769427
• 출원인 : Carbon (Shenzhen) Medical Device Co, Ltd.
• 특허번호 :
• IPC : A61B-034/10(2006.01);A61B-010/02(2006.01);A61B-017/34(2006.01);G06T-007/12(2006.01);G06T-007/168(2006.01);G06T-007/174(2006.01);G06T-007/38(2006.01);G06T-019/00(2006.01);

An automatically adjusting seismic restraint system for nuclear fuel storage in one embodiment comprises a free-standing first fuel storage component (FSC) configured to contain nuclear fuel, and a stationary second FSC configured to receive the first fuel storage component. An inter-body gap formed between the FSCs includes at least one seismic restraint assembly. The assembly includes a stationary wedge member fixedly coupled to the second FSC and a movable loose wedge member engaged with and supported in place by the stationary wedge member. The stationary wedge member defines an inclined load bearing surface slideably engaged with a mating inclined load bearing surface of the loose wedge member. During a seismic event or thermal expansion of the first FSC, the first FSC moves towards the second FSC which shrinks the inter-body gap and the loose wedge member is vertically displaced relative to the stationary wedge member while maintaining engagement therewith.

• 출원번호 : 18770009
• 출원인 : Holtec International
• 특허번호 :
• IPC : G21C-019/07(2006.01);G21C-009/04(2006.01);G21C-019/40(2006.01);G21F-005/08(2006.01);

Various aspects as described herein are directed to a radiative cooling apparatuses and methods for cooling an object. As consistent with one or more embodiments, a radiative cooling apparatus includes an arrangement of a plurality of different material located at different depths along a depth dimension relative to the object. The plurality of different material includes a solar spectrum reflecting portion configured and arranged to suppress light modes, thereby inhibiting coupling of the incoming electromagnetic radiation, of at least some wavelengths in the solar spectrum, to the object at a range of angles of incidence relative to the depth dimension. Further, the plurality of material includes a thermally-emissive arrangement configured and arranged to facilitate, simultaneously with the inhibiting coupling of the incoming electromagnetic radiation, the thermally-generated electromagnetic emissions from the object at the range of angles of incidence and in mid-IR wavelengths.

• 출원번호 : 18770522
• 출원인 : Raman, Aaswath Pattabhi
• 특허번호 :
• IPC : F28F-013/18(2006.01);B60H-001/32(2006.01);F24F-005/00(2006.01);F25B-023/00(2006.01);F28F-003/12(2006.01);F28F-013/00(2006.01);

A molten salt reactor system includes a fluid level control system configured to circulate a molten salt through a molten salt loop including an experimental tank, a sump tank, and a drain tank. The fluid level control system further includes a plurality of level sensors, pressure transducers, and electronic pressure regulators fluidically coupled with the fuel salt system. The fluid level control system is configured to receive cover gas pressures in the headspaces of the tanks and calculate target fluid height setpoints for each of the tanks. The fluid level control system further invokes the electronic pressure regulator to iteratively adjust the cover gas pressures of the tanks to achieve and maintain a target fluid level in the experimental tank.

• 출원번호 : 18769565
• 출원인 : MAKAREWICZ, Joseph
• 특허번호 :
• IPC : G21C-023/00(2006.01);G21C-003/54(2006.01);G21C-017/035(2006.01);G21C-019/02(2006.01);G21C-019/28(2006.01);

Provided herein are compounds, compositions and methods for treating and preventing diseases and disorders, comprising administering to patients therapeutically effective amounts of cysteine-dependent inverse agonists of the nuclear receptor RORγ/RORγt. In some such embodiments, the inverse agonists bind to cysteine 476 of a nuclear receptor RORγ in the patient. Also provided are methods, as well as compounds and compositions, for modulating the activity of RORγ and RORγt by binding to the allosteric binding site through a covalent bond. In some aspects, the present disclosure relates to using compounds containing Michael acceptor groups which bind to a cysteine residue in the allosteric binding site such as cysteine 476 in RORγ.

• 출원번호 : 18770647
• 출원인 : REATA PHARMACEUTICALS, INC.
• 특허번호 :
• IPC : C07D-401/04(2006.01);C07D-403/04(2006.01);

• 출원번호 : 24188103.6
• 출원인 : Marabu GmbH &Co. KG;
• 특허번호 :
• IPC : C09D-011/101(2014.01);C09D-011/103(2014.01);C09D-011/102(2014.01);C09D-011/30(2014.01);C09D-004/06(2006.01);

• 출원번호 : US2024/037508
• 출원인 : ABILENE CHRISTIAN UNIVERSITY
• 특허번호 :
• IPC :

Provided is an X-ray CT apparatus capable of maintaining image quality of a tomographic image while reducing an emission dose to a site having high radiation sensitivity.An X-ray CT apparatus includes an X-ray source that emits an X-ray to a subject, an X-ray detector that detects the X-ray transmitted through the subject, a rotating plate that causes the X-ray source and the X-ray detector to rotate around the subject, an image generation section that generates a tomographic image of the subject based on a detection signal of the X-ray detector, and a controller that controls each unit, in which the controller has a modulation pattern setting section that sets a modulation pattern used for modulation of an emission dose, which is an X-ray dose emitted from the X-ray source while the rotating plate rotates, such that the emission dose to a site having high radiation sensitivity of the subject is reduced more than the emission dose to other sites, and a modulation pattern adjustment section that adjusts the modulation pattern based on an upper limit speed, which is an upper limit of a modulation speed of the emission dose.

• 출원번호 : 24188149.9
• 출원인 : FUJIFILM Corporation
• 특허번호 :
• IPC : A61B-006/03(2006.01);A61B-006/40(2024.01);A61B-006/00(2024.01);

A stable light source is described, which is configured for multi-output spectrally matched and equivalent intensity radiation. The source includes a first splitter configured to receive and split input radiation into first transmissive and reflective portions; second splitters configured to receive and further split each of the first transmissive and reflective portions into second transmissive and reflective portions; and combiners configured to combine the second transmissive and reflective portions into different outputs with mixed transmissive and reflective portions. The mixed transmissive and reflective portions are configured such that outputs together form the spectrally matched and equivalent intensity radiation. This may be used to calibrate highly accurate detectors, for example, and/or for other purposes. An integrating sphere may be included (e.g., instead of and/or in addition to the splitter(s) and combiner(s)).

• 출원번호 : EP2024/069761
• 출원인 : ASML NETHERLANDS B.V.
• 특허번호 :
• IPC : G02B-027/10(2006.01);G02B-006/26(2006.01);G02B-027/14(2006.01);

The present invention refers to a cleaning system (100) for cleaning a carrier (105) for semi-conductor substrates or at least a surface of the carrier (105), comprising: a first chamber (110) and a second chamber (120), wherein the first chamber (110) and the second chamber (120) are in fluid-communication with each other, wherein the second chamber (120) is con- figured to accommodate the carrier (105); an input fluid supply (130) configured to provide an input fluid (135) to the first chamber (110); a radiation source (140) configured to provide ra- diation of at least one predetermined wavelength within the first chamber (110) and config- ured to create a cleaning fluid (145) comprising a plasma and/or ozone and/or atomic oxygen by means of exposing the input fluid (135) in the first chamber (110) to the radiation; a clean- ing fluid transfer unit (150) configured to transfer the cleaning fluid from the first chamber (110) to the second chamber (120) for cleaning the carrier (105) or at least the surface of the carrier (105) provided in the second chamber (120) and configured to subject the carrier (105) or at least the surface of the carrier (105) to the cleaning fluid in the second chamber (120).

• 출원번호 : EP2024/069694
• 출원인 : BROOKS AUTOMATION (GERMANY) GMBH
• 특허번호 :
• IPC : H01L-021/67(2006.01);H01J-037/32(2006.01);