An example method includes obtaining one or more three dimensional computer models that model geometric and material properties of a component (12), and model beam properties of a beam (16) of radiation to be applied to the component (12); utilizing the one or more three dimensional computer models to obtain simulated radiation imaging data, which includes simulated elastic scattering data, resulting from a simulated application of the beam (16) having the beam properties on a plurality of discretized samples (82) of the component (12), and which accounts for sequential interactions of rays of the beam (16) with multiple ones of the plurality of discretized samples (82); obtaining actual radiation imaging data, which includes actual elastic scattering data, of an output beam pattern (20) caused by application of a non-simulated beam (16) of radiation having the beam properties to the component (12); and performing at least one of: determining whether an anomaly exists in a crystalline structure of the component (12) based a comparison of the simulated elastic scattering data to the actual elastic scattering data; and modifying the actual radiation imaging data based on the simulated elastic scattering data to at least partially remove the actual elastic scattering data from the actual radiation imaging data. A corresponding system (10) is also disclosed.

• 출원번호 : 24174169.3
• 출원인 : RTX Corporation
• 특허번호 :
• IPC : G01N-023/2055(2018.01)

A module (1) of a solar collector comprises a container (2) transparent to a light radiation which has a vacuum gap delimiting a primary volume. The module (1) also comprises a conduit (3) for conveying a vector fluid and a heat energy accumulating material (4). The latter is arranged between the conduit (3) and the container (2) and it is configured to accumulate a set quantity of heat energy arising from the light radiation. The module (1) further comprises a light radiation absorbing element interposed between the heat energy accumulating material (4) and the container (2) and configured to absorb solar radiation and reduce a possible dispersion due at least to the refraction phenomenon. The absorbing element is also configured to convert at least part of the light radiation absorbed into a quantity of heat energy. In particular, the heat energy accumulating material (4) is configured to absorb and accumulate the quantity of heat energy deriving from the light radiation and, further, to transfer said quantity of heat energy to said conduit (3). The heat energy accumulating material (4) extends along the container (2) until it protrudes therefrom so as to define a protruding portion (40) outside the primary volume.

• 출원번호 : 24174119.8
• 출원인 : Spinazza, Roberto
• 특허번호 :
• IPC : F24S-010/40(2018.01);F24S-010/70(2018.01);F24S-060/00(2018.01);F24S-080/54(2018.01);F24S-020/40(2018.01);F24S-023/70(2018.01);F24S-070/12(2018.01);F24S-070/20(2018.01);F24S-010/75(2018.01);F24S-020/00(2018.01);

본 발명은 천장형 복사 난방 장치를 개시한다. 본 발명의 천장형 복사 난방 장치는: 측이 개방되는 하우징; 상기 하우징의 하측 개구부를 덮도록 설치되고, 아래를 향하여 볼록하게 형성되고, 복사열을 방열하도록 열전도성 재질로 형성되는 방열판; 상기 방열판을 가열하도록 상기 방열판에 설치되는 히터; 및 상기 하우징과 상기 방열판의 내부를 둘러싸도록 설치되고, 상기 히터에서 방사되는 복사열을 상기 방열판 측으로 반사하는 반사판;을 포함한다.

• 출원번호 : 10-2024-0058276
• 출원인 : 주식회사 보성산업
• 특허번호 : 10-2740638-0000
• IPC : F24C-007/04;F24C-015/08;F24C-015/22;F24D-013/02;

The present disclosure provides polymeric nanoparticle compositions and methods of using the same to treat senescence-associated pathologies and improving tumor responses to anti-cancer therapies, such as immunotherapy (, immune checkpoint blockade therapy), adoptive cell therapy, chemotherapy, or radiation therapy and the like. Also disclosed herein are methods of using the polymeric nanoparticle compositions of the present technology to improve tissue function after organ transplantation, hip replacement etc. In some embodiments, the polymeric nanoparticles described herein have an affinity to P-selectin and comprise a senolytic or senomorphic drug.

• 출원번호 : US2024/027510
• 출원인 : MEMORIAL SLOAN-KETTERING CANCER CENTER;MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES;SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;
• 특허번호 :
• IPC : A61K-031/4965(2006.01);A61K-031/5375(2006.01);A61K-047/26(2006.01);A61K-047/38(2006.01);A61K-047/42(2017.01);A61K-009/51(2006.01);A61P-025/28(2006.01);A61P-035/00(2006.01);A61P-009/10(2006.01);

It is disclosed a computer-implemented system and method of predicting and diagnosing osteoporosis on the basis of magnetic resonance imaging techniques. Particularly, the method of the invention is a reliable, reproducible and sensitive method for predicting or diagnosing osteoporosis from magnetic resonance images, through a simple and quick statistical processing, i.e. by only statistically correlating recorded MRI of a subject to recorded MRI of reference groups, independently of other standard techniques such as, for example, MOC, QCT, DXA, or clinical diagnosis of osteoporosis. In this regard, any patient who undergoes magnetic resonance imaging for reasons independent of osteoporosis, could anyway receive diagnostic information also on his/her medical status concerning osteoporosis, without additional investigations or tests and without the use of ionizing radiation, regardless of previous suspicion of osteoporotic pathology. This is very precious and desirable as, in this way, it is possible to early identify patients at risk of osteoporosis or with the pathology already in progress, notwithstanding the asymptomatic nature of osteoporosis. Moreover, the overall method of the invention is very convenient insofar as neither the patient nor the national health system incur additional costs.

• 출원번호 : IB2024/054252
• 출원인 : M-SCORE BONE HEALTH S.R.L.
• 특허번호 :
• IPC : A61B-005/055(2006.01);A61B-005/00(2006.01);

An ink jet recording method includes ejecting a radiation-curable ink jet composition to a recording medium from an ink jet head, and curing the ink jet composition ejected to the recording medium by irradiating with radiation from a LED irradiator having a peak wavelength of 250 to 310 nm to form a cured coating film. The ink jet composition contains a polymerizable compound and an α-hydroxyketone-based initiator.

• 출원번호 : 18653089
• 출원인 : SAITO, Toru
• 특허번호 :
• IPC : B41M-005/00(2006.01);B41J-011/00(2006.01);C09D-011/037(2006.01);C09D-011/101(2006.01);C09D-011/107(2006.01);C09D-011/322(2006.01);C09D-011/38(2006.01);

Pituitary tumors may be reduced in size by administration of relacorilant. Pituitary tumors include, without limitation, non-secreting tumors, hormone-secreting tumors, adenomas, and carcinomas. Relacorilant administration may be effective to reduce hormone secretion from a hormone-secreting pituitary tumor, e.g., to reduce adrenocorticotrophic hormone (ACTH) secretion. A pituitary tumor may be imaged before and/or after relacorilant administration. Relacorilant may be administered independent of surgery, and before, during, or after surgery to treat a pituitary tumor. Relacorilant may aid or improve surgical outcomes, and may reduce the size or growth of pituitary tumor tissue before surgery, and any tumor tissue remaining following surgical treatment. Relacorilant may be orally administered for the treatment of pituitary tumors. Relacorilant may be orally administered to a fasted patient, or to a fed patient. Relacorilant may be administered in conjunction with other pituitary tumor targeting treatments, including surgical treatments, radiation treatments, chemotherapy for carcinomas, and other pharmaceutical treatments.

• 출원번호 : 18653070
• 출원인 : Corcept Therapeutics Incorporated
• 특허번호 :
• IPC : A61K-031/444(2006.01);A61B-017/3205(2006.01);A61N-005/10(2006.01);A61P-035/00(2006.01);

A passenger vehicle, comprising: a frame of a vehicle; a passenger compartment of the vehicle, including a selected region suitable for presence of people; a magnetic field source configured such that upon electrification, magnetic field radiation is caused in the selected region; a plurality of magnetic field sensors arranged along generally intersecting planes for providing magnetic field sensing data along at least two axes within the selected region; and at least one circuit mounted in the vehicle and electrically connected to the plurality of magnetic field sensors, the at least one circuit being configured to measure the magnetic field radiation in the selected region.

• 출원번호 : 18653770
• 출원인 : SAFEFIELDS TECHNOLOGIES LTD.
• 특허번호 :
• IPC : G01R-033/00(2006.01);B60R-016/023(2006.01);G01R-033/07(2006.01);

Ocular antimicrobial compositions and methods and method of use thereof are provided. The compositions incorporate photoactive heterojunction materials can be incorporated into a suitable carrier, alone or in combination with an enzyme capable of generating ROS upon contact with the eye for the treatment of ocular conditions. The method includes contacting the eye of a subject in need thereof, the subject has or has been diagnosed with microbial keratitis, with an effective amount of the disclosed composition. The method further includes contacting the composition in the subject's eye with near infrared radiation (NIR).

• 출원번호 : 18653590
• 출원인 : Chan, Yau Kei
• 특허번호 :
• IPC : A61K-038/44(2006.01);A61K-009/00(2006.01);A61K-038/06(2006.01);A61K-038/07(2006.01);A61K-038/08(2006.01);A61K-041/17(2006.01);A61P-027/02(2006.01);A61P-031/04(2006.01);

A method of making a polyimide (PI)-based material. In one embodiment, the method begins by dispersing a polyamic acid (PAA) oligomer and photo-initiator into a photo-reactive monomer to form a liquid resin. In contrast to the above-described prior art, the liquid resin is substantially devoid of any non-reactive solvents. Electromagnetic radiation is then applied (e.g., in a 3D printing operation) to solidify the liquid resin and to substantially form a interpenetrating polymer network (IPN) in which the PAA oligomer is entangled within the network formed by the photo-reactive monomer but remains substantially independent and un-crosslinked from the PAA oligomer. Thereafter, the PAA-based IPN is thermally cycled to form a polyimide-based IPN.

• 출원번호 : 18653643
• 출원인 : Walker, David A.
• 특허번호 :
• IPC : C08L-033/26(2006.01);B29B-013/02(2006.01);B29C-064/129(2006.01);B29K-033/00(2006.01);B29K-079/00(2006.01);B29K-105/00(2006.01);B33Y-070/00(2006.01);C08G-073/10(2006.01);