Aspects of the present disclosure provide a method for fabricating a grating coupler. For example, the method can include providing a substrate, forming a plurality of grating elements and a photosensitive material above the substrate, and projecting actinic radiation of varied intensities to expose different regions of the photosensitive material, causing the photosensitive material to generate a solubility-changing agent. The method can also include removing the solubility-changing agent. The actinic radiation of varied intensities can correspond to depths of grooves between the grating elements.

• 출원번호 : US2024/045870
• 출원인 : TOKYO ELECTRON LIMITED;TOKYO ELECTRON U.S. HOLDINGS, INC.;
• 특허번호 :
• IPC : G02B-006/00(2006.01);G02B-005/18(2006.01);G02B-027/01(2006.01);

A decorative sheet includes: a primary film layer; and a surface protective layer, wherein the surface protective layer has a gloss level of 15 or less, the surface protective layer includes a ridged portion projecting in a ridged pattern from a surface of the surface protective layer to form an uneven shape on the surface, the surface protective layer contains an ionizing radiation-curable resin as a main material, the ionizing radiation-curable resin contains, as a main component, a tetrafunctional acrylic resin having a repeating structure, the number of repetitions of the repeating structure is 12 or more, a content of vinyl groups contained in the ionizing radiation-curable resin is 20% or less relative to carbonyl groups contained in the ionizing radiation-curable resin, and the uneven shape of the surface protective layer (5) has RSm/Ra in a range of 10 or greater and 300 or less.

• 출원번호 : 18828345
• 출원인 : TOPPAN HOLDINGS INC.
• 특허번호 :
• IPC : C09D-135/02(2006.01);C08F-022/10(2006.01);C08F-022/20(2006.01);C09D-004/00(2006.01);C09D-005/28(2006.01);C09D-007/40(2006.01);

A system provides for an ability to automatically identify one or more chemical components of a sample, especially a biological fluid sample, based on analysis of spectral data by at least one artificial intelligence module. The artificial intelligence module is able to be trained on a plurality of spectral data samples having known concentrations of individual chemicals and elements. The system is preferably used for spectral techniques such as UV/vis and near-infrared (NIR) spectrophotometry, but is also able to be used for other forms of spectroscopic techniques, including mass spectrometry, infrared (IR) spectrometry, X-ray spectroscopy, Raman spectrometry, or nuclear magnetic resonance (NMR) spectrometry.

• 출원번호 : 18828382
• 출원인 : Vionix Biosciences Inc.
• 특허번호 :
• IPC : G16B-040/10(2019.01);G16H-010/40(2018.01);G16H-015/00(2018.01);G16H-050/70(2018.01);

Disclosed herein are methods of treatments with a telomerase-mediated telomere-targeting drug, 6-thio-2′-deoxyguanosine (6-thio-dG), checkpoint inhibitors and/or radiation therapy for treating cancers. eads to tumor regression in innate and adaptive immune-dependent manners in syngeneic and humanized mouse cancer models.

• 출원번호 : 18829162
• 출원인 : The Board of Regents of The University of Texas System
• 특허번호 :
• IPC : A61K-031/7076(2006.01);A61N-005/00(2006.01);A61P-035/00(2006.01);C07K-016/28(2006.01);

A sensor including a light-receiving element; and an optical element that includes near infrared absorbing dichroic substance. The optical element has an absorption axis with respect to near infrared light in an in-plane direction. When linearly polarized light of near infrared light orthogonal to the absorption axis is radiated from a normal direction of the optical element and from a direction inclined by 45° from the normal direction at an azimuthal angle orthogonal to the absorption axis, an absorbance during the radiation from the direction inclined by 45° from the normal direction is more than an absorbance during the radiation from the normal direction.

• 출원번호 : 18828794
• 출원인 : FUJIFILM Corporation
• 특허번호 :
• IPC : G06V-040/13(2006.01);G02B-005/20(2006.01);

Systems and methods for positioning in medical systems are provided. The system may obtain data associated with a scanning range of a subject. The system may also obtain an image of the subject on a couch of a medical radiation device. The image may be acquired by an imaging device when the couch is at a first position. The system may determine a position of the scanning range of the subject in the image. The system may further cause, based on the position of the scanning range in the image, the couch to move to a second position. The scanning range of the subject may be in a radiation region of the medical radiation device when the couch is located at the second position.

• 출원번호 : 18827885
• 출원인 : SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
• 특허번호 :
• IPC : A61B-006/04(2006.01);A61B-005/055(2006.01);A61B-006/00(2006.01);A61B-006/46(2006.01);A61B-006/58(2006.01);G06F-003/0482(2006.01);G06F-003/04847(2006.01);G06T-007/00(2006.01);G06T-007/50(2006.01);G06T-007/70(2006.01);

Apparatus, systems, and methods are provided for optimizing radiation therapy to a patient to treat cardiac arrhythmias. The system generally includes an ultrasound device placed within the esophagus to image and map cardiac structures in real-time. The system may also control the ventilation of the patient to optimize ultrasound monitoring and radiation delivery. The device in the esophagus is designed to position and monitor the esophagus and/or nearby structures to optimize radiation delivery to targets while minimizing radiation to other key structures. In addition, different ablation technologies may be delivered from within the esophagus to ablate certain tissues that cannot be safely ablated with radiation therapy. Finally, the esophageal device may have electrical or magnetic properties that can be used to guide the radiation therapy.

• 출원번호 : 18828736
• 출원인 : Kaiser, Daniel Walter
• 특허번호 :
• IPC : A61B-018/14(2006.01);A61B-008/06(2006.01);A61B-008/08(2006.01);A61B-008/12(2006.01);A61B-018/00(2006.01);

A magnetic field sensor may be provided comprising at least one diamond which comprises at least one nitrogen-vacancy-center. The magnetic field sensor comprises further at least one optical resonator. The diamond is arranged in the optical resonator. At least one pump laser is provided which is configured to illuminate the diamond with laser radiation having a wavelength of about 480 nm to about 637 nm. The sensor comprises further at least one measuring laser configured to illuminate the diamond with laser radiation having a wavelength from 750 nm to 1040 nm or from 1044 nm to 1500 nm, wherein the sensor comprises at least one detector configured to detect the absorption of the laser radiation of the measuring laser in the diamond. Methods are provided for detecting a magnetic field by the magnetic field sensor.

• 출원번호 : 18828762
• 출원인 : Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
• 특허번호 :
• IPC : G01R-033/032(2006.01);G01R-029/08(2006.01);G01R-033/26(2006.01);

Systems and methods for improved radiation treatment planning can employ hierarchical constrained optimization with relaxed constraints also referred to herein after as expedited hierarchical constrained optimization (ECHO). The systems and methods described herein employ a combination of constrained optimization and a correction loop involving unconstrained optimization to enhance the speed and efficiency of the radiation treatment planning process and improve the accuracy and quality of resulting radiation treatment plans. The use of a hierarchical constrained optimization approach leads to less complex and faster to solve optimization problems. The correction loop allows for compensating for optimization error associated with the sequence of constrained optimizations by incorporating such error in an unconstrained optimization. Hard and soft dose volume constraints can be efficiently incorporated.

• 출원번호 : 18828870
• 출원인 : ZAREPISHEH, Masoud
• 특허번호 :
• IPC : A61N-005/10(2006.01)

Systems and methods for imaging in the short wave infrared (SWIR), photodetectors with low dark current and associated circuits for reducing dark currents and methods for generating image information based on data of a photodetector array. A SWIR imaging system may include a pulsed illumination source operative to emit radiation pulses in the SWIR band towards a target resulting in reflected radiation from the target; (b) an imaging receiver including a plurality of Ge PDs operative to detect the reflected SWIR radiation and a controller, operative to control activation of the receiver for an integration time during which the accumulated dark current noise does not exceed the time independent readout noise.

• 출원번호 : 18827906
• 출원인 : Prosper Shalibo, Yoni
• 특허번호 :
• IPC : H01S-005/06(2006.01);B32B-018/00(2006.01);C04B-035/495(2006.01);G01S-007/484(2006.01);H01S-003/06(2006.01);H01S-003/0941(2006.01);H01S-003/113(2006.01);H01S-003/131(2006.01);H01S-003/16(2006.01);H01S-005/00(2006.01);