This radiation-sensitive composition contains a polymer which has a structural unit (I) containing an aromatic ring having a substituent and a lactone structure, a cyclic carbonate structure, a sultone structure, or a combination thereof, and in which the solubility in a developing solution changes due to an action of an acid.

• 출원번호 : JP2025/028360
• 출원인 : JSR CORPORATION
• 특허번호 :
• IPC : G03F-007/039(2006.01);C08F-012/32(2006.01);C08F-020/30(2006.01);C08F-212/00(2006.01);C08F-212/08(2006.01);G03F-007/20(2006.01);

PROBLEM TO BE SOLVED: To provide methods for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.SOLUTION: A crystalline hydrate of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide is provided. Preferably, the hydrate is a hemihydrate. Preferably, the crystalline hydrate has an X-ray powder diffraction pattern characterized by peaks at 13.4±0.2, 15.1±0.2, and 21.7±0.2°2θ when measured at about 25°C with monochromatic Kα1 radiation.SELECTED DRAWING: None

• 출원번호 : 2025133176
• 출원인 : ABBVIE INC
• 특허번호 :
• IPC : C07D-487/14(2006.01);A61K-031/4985(2006.01);A61P-001/04(2006.01);A61P-017/06(2006.01);A61P-019/08(2006.01);A61P-017/02(2006.01);A61P-017/14(2006.01);A61P-037/08(2006.01);A61P-037/02(2006.01);A61P-043/00(2006.01);A61K-047/12(2006.01);A61K-047/38(2006.01);A61K-009/06(2006.01);

The present invention relates to a composition for protecting against radiation-induced salivary gland damage, the composition comprising an MGEA5 inhibitor and, more specifically, to a composition for protecting against or mitigating radiation, the composition comprising an MGEA5 inhibitor so as to capable of preventing the removal of O-GlcNAc, bound to a protein and involved in radiation-induced cell damage and death, to inhibit the phosphorylation of a target protein and thereby suppress the activity thereof. The composition can thus be used to prevent, alleviate, or treat radiation therapy-induced salivary gland damage.

• 출원번호 : KR2025/012005
• 출원인 : KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION;
• 특허번호 :
• IPC : A61K-031/7056(2006.01);A61K-031/429(2006.01);A61K-031/496(2006.01);A61K-031/4523(2006.01);A61K-031/7088(2006.01);A61P-001/00(2006.01);

A method of fabricating a semiconductor device includes providing a first substrate and forming a resist layer over the first substrate. In some embodiments, the method further includes performing an exposure process to the resist layer. The exposure process includes exposing the resist layer to a radiation source through an intervening mask. In some examples, the intervening mask includes a second substrate, a multi-layer structure formed over the second substrate, a capping layer formed over the multi-layer structure, and an absorber layer disposed over the capping layer. In some embodiments, the absorber layer includes a first main pattern area and an opening area spaced a distance from the first main pattern area. In various examples, the method further includes, after performing the exposure process, developing the exposed resist layer to form a patterned resist layer.

• 출원번호 : 19294442
• 출원인 : LIAO, Chi-Hung
• 특허번호 :
• IPC : H01L-021/027(2006.01);G03F-001/22(2012.01);G03F-001/24(2012.01);G03F-001/54(2012.01);G03F-007/20(2006.01);H01L-021/033(2006.01);

The compositions and methods described herein include culturing an oocyte, an ooplast, or an embryo (e.g., an early-stage embryo) in a culture media with a GPCR ligand. Such oocytes can be used for somatic cell nuclear transfer (SCNT) and subsequent cloning and implantation into a recipient female.

• 출원번호 : US2025/041248
• 출원인 : TAURGEN THERAPEUTICS, LLC
• 특허번호 :
• IPC : C12N-015/873(2010.01);A01K-067/0273(2024.01);C12N-015/06(2006.01);

PROBLEM TO BE SOLVED: To provide methods for preparing (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide, solid state forms thereof, and corresponding pharmaceutical compositions, methods of treatment (including treatment of rheumatoid arthritis), kits, methods of synthesis, and products-by-process.SOLUTION: A crystalline hydrate of (3S,4R)-3-ethyl-4-(3H-imidazo[1,2-a]pyrrolo[2,3-e]pyrazin-8-yl)-N-(2,2,2-trifluoroethyl)pyrrolidine-1-carboxamide is provided. Preferably, the hydrate is a hemihydrate. Preferably, the crystalline hydrate has an X-ray powder diffraction pattern characterized by peaks at 13.4±0.2, 15.1±0.2, and 21.7±0.2°2θ when measured at about 25°C with monochromatic Kα1 radiation.SELECTED DRAWING: None

• 출원번호 : 2025133177
• 출원인 : ABBVIE INC
• 특허번호 :
• IPC : C07D-487/14(2006.01);A61K-031/4985(2006.01);A61P-019/02(2006.01);A61P-017/06(2006.01);A61P-019/08(2006.01);A61P-017/14(2006.01);A61P-037/08(2006.01);A61P-037/02(2006.01);A61P-017/00(2006.01);A61K-009/06(2006.01);A61K-047/12(2006.01);C07D-207/16(2006.01);A61K-047/38(2006.01);A61P-001/04(2006.01);

PROBLEM TO BE SOLVED: To provide a method for planarizing a substrate.SOLUTION: A method for planarizing a substrate includes: receiving a substrate having microfabricated structures that differ in height across a working surface of the substrate that define a non-planar topography; depositing a first layer that includes a solubility-shifting agent on the working surface of the substrate by spin-on deposition in a non-planar fashion; exposing the first layer to a first pattern of actinic radiation based on the topography; developing the first layer using a predetermined solvent; and depositing a second layer over the working surface of the substrate that has a greater planarity as compared to the first layer prior to developing the first layer. The first pattern of radiation changes a solubility of the first layer such that upper regions of the non-planar topography of the first layer are soluble to the predetermined solvent.SELECTED DRAWING: Figure 1D

• 출원번호 : 2025133001
• 출원인 : TOKYO ELECTRON LTD;TOKYO ELECTRON U S HOLDINGS INC;
• 특허번호 :
• IPC : G03F-007/38(2006.01);H01L-021/027(2006.01);G03F-007/20(2006.01);

The present invention relates to a head elevation and support device, in particular a head elevation and support device for use with a nuclear magnetic resonance (NMR) device. The head elevation and support device being shaped and configured to elevate and support a head of a patient for neuroimaging by a NMR medical device.

• 출원번호 : IB2025/058045
• 출원인 : WELLUMIO LIMITED
• 특허번호 :
• IPC : A61B-006/04(2006.01);A61B-005/055(2006.01);A61B-006/00(2024.01);A61B-006/40(2024.01);A61B-006/50(2024.01);A61B-090/14(2016.01);A61G-007/10(2006.01);A61G-013/12(2006.01);

PRIVACY GLASS A privacy glass (100) includes: a first transparency (102) having a first major surface (104) and an opposing second major surface (106), the No. 1 surface (104) defining an exterior of the privacy glass; a second transparency (108) having a third major surface (110) and an opposing fourth major surface (112), the No. 4 surface (112) defining an interior of the privacy glass; and an interlayer (114) positioned between the No. 2 surface (106) and the No. 3 surface (110). A solar control coating (116) is arranged over the No. 2 surface (106), the solar control coating configured to reflect at least 50% of solar infrared radiation. At least one of the interlayer (114) and the second transparency (108) is tinted so that the privacy glass (100) has a visible transmittance of less than 30%. The solar control coating (114) is selected such that the privacy glass (100) has an a* of from -4 to 0.5 and an b* of from -4 to 2.

• 출원번호 : US2025/041008
• 출원인 : VITRO FLAT GLASS LLC
• 특허번호 :
• IPC : B32B-017/10(2006.01)

A device surrounded by ambient air that radiantly heats or radiantly cools subjects. The device includes a planar heat exchanger with at least one radiantly active face and which at least partially transmits visible radiation, a support frame, and one or more membranes that create sealed, planar, gas-filled cavities that isolate radiantly active faces of the planar heat exchanger from contact with the ambient air.

• 출원번호 : US2025/041023
• 출원인 : AIL RESEARCH INC.
• 특허번호 :
• IPC : F24F-005/00(2006.01);F24D-005/10(2006.01);F28F-013/18(2006.01);F25B-023/00(2006.01);F24F-013/22(2006.01);