PROBLEM TO BE SOLVED: To develop pharmaceutical crystals suitable for formulation of a compound.SOLUTION: Polymorphic forms of a compound and a preparation method therefor and an application thereof are disclosed. A crystal form III of a compound A uses Cu-Kα radiation, and X-ray powder diffraction expressed at 2θ angles has characteristic peaks at 12.15±0.20°, 15.98±0.20°, 16.62±0.20°, 17.14±0.20°, 24.32±0.20°, and 26.08±0.20°. A crystal form VII of the compound A uses Cu-Kα radiation, and X-ray powder diffraction expressed at 2θ angles has characteristic peaks at 12.94±0.20°, 14.41±0.20°, 15.64±0.20°, 17.25±0.20°, 21.75±0.20°, and 24.23±0.20°. The polymorphic forms prepared by the present invention are good in stability, and can be stably stored under the conditions of high temperature and low relative humidity.SELECTED DRAWING: Figure 28
- 출원번호 : 2025138999
- 출원인 : WUHAN CREATERNA SCIENCE & TECHNOLOGY CO LTD
- 특허번호 :
- IPC : C07D-401/12(2006.01);A61K-031/4439(2006.01);A61P-001/04(2006.01);A61P-035/00(2006.01);A61P-031/04(2006.01);A61P-025/00(2006.01);A61P-037/02(2006.01);A61P-011/06(2006.01);A61P-003/04(2006.01);A61P-019/06(2006.01);A61P-009/10(2006.01);A61P-037/08(2006.01);A61P-043/00(2006.01);