Provided herein are methods and compositions for disrupting expression of nuclear receptor interacting protein 1 (Nrip1) in adipose cells. and methods of use of such adipose cells for treating, or reducing risk of, a condition associated with an elevated body mass index (BMI).

• 출원번호 : 18672796
• 출원인 : Czech, Michael P.
• 특허번호 :
• IPC : C12N-009/22(2006.01);A61K-035/35(2006.01);A61P-003/04(2006.01);C12N-005/077(2006.01);C12N-015/11(2006.01);C12N-015/90(2006.01);

The present invention is a system for providing accurate image-guided localization of a radiation target using digital image acquisition with real time data analysis utilizing a radiation device, directing a beam of radiation through a sample reflecting onto a film screen and reflecting an image from the film screen onto a mirror that will project the image from the mirror to a bean splitter where it is captured by a camera operatively associated with a computer device.

• 출원번호 : 18673272
• 출원인 : Wu, Xiaodong
• 특허번호 :
• IPC : A61N-005/10(2006.01)

A vibration estimation system for estimating vibration of at least one target, comprising a transceiver; a radiating antenna arranged and configured to radiate an electromagnetic transmit signal from the transceiver in a transmission direction with a radiation pattern comprising a main lobe having a distance-dependent extension in a plane perpendicular to the transmission direction, and to return to the transceiver an electromagnetic reflection signal resulting from reflection of the transmit signal at the at least one target, when the at least one target is located within the distance-dependent extension of the main lobe of the transmit signal; processing circuitry coupled to the transceiver and configured to estimate the vibration of the target based on a difference between the transmit signal and the reflection signal; and an aiming arrangement arranged and configured to provide a visible aiming pattern visually indicating the distance-dependent extension of the main lobe of the transmit signal.

• 출원번호 : 18672111
• 출원인 : Delin, Håkan
• 특허번호 :
• IPC : G01M-005/00(2006.01);G01S-007/35(2006.01);G01S-013/36(2006.01);G01S-013/88(2006.01);

A high-temperature gas-cooled reactor (HTGR) core is disclosed which includes a plurality of nuclear fuel kernels encapsulated by i) solid structures; and ii) porous structures, wherein the solid structures and the porous structures form a heterogeneous tileable repeating assembly including a channel for moving heat out of the HTGR core, wherein a ratio of in-channel porosity to in-channel tortuosity of the assembly is between about 0.2 to about 0.5, wherein the in-channel tortuosity is between about 1.0 and 1.6, and wherein total solid fraction of the assembly is between about 0.6 to about 0.85.

• 출원번호 : 18672891
• 출원인 : Purdue Research Foundation
• 특허번호 :
• IPC : G21C-015/253(2006.01);G21C-005/12(2006.01);G21C-015/16(2006.01);

The invention relates to a protective label for a container (200), having: - a flat barrier layer (103) which produces a barrier function against the passage of a fluid and/or electromagnetic radiation, - a first label section (101) which is designed to be secured to a first container section (201) of the container (200), and - a second label section (102) which adjoins the first label section (101) along a first direction (104) and which is designed to be secured to a second container section (202) of the container (200), wherein the first container section (201) and the second container section (202) are oriented at an angle to each other, and the second label section (102) has a plurality of label fingers (106, 107, 108) which can be tilted relative to one another. Each of the label fingers (106, 107, 108) has an adhesive region (111) at least at one end (109) which faces away from the first label section (101) along the first direction (104), and the label fingers (106, 107, 108) are designed to cover the second container section (102) when the label fingers are applied.

• 출원번호 : EP2024/064157
• 출원인 : SCHREINER GROUP GMBH &CO. KG;
• 특허번호 :
• IPC : G09F-003/02(2006.01);G09F-003/10(2006.01);

The invention relates to a substrate with a mark consisting of microscopic metallurgical structures (3) arranged randomly on the surface of the substrate and having at least one physical and/or chemical property different from the rest of the substrate. At least one structure comprises an element such that exposing the mark to radiation or to an external electrical or magnetic field or to a chemical attack or to mechanical, thermal or electrical stress induces a temporary or permanent change of at least one physical or chemical property of the structure. The structures may be a different first alloy (31) and second alloy (32). The alloy 31 changes colour in a stable and definitive manner after exposure to laser radiation while the alloy 32 has a high reflectivity and is therefore stable to laser exposure.

• 출원번호 : IB2024/055025
• 출원인 : UNIVERSITÉDE GENEVE;
• 특허번호 :
• IPC : B42D-025/305(2014.01);B42D-025/36(2014.01);B42D-025/373(2014.01);B42D-025/41(2014.01);B42D-025/445(2014.01);

Described herein, are methods of determining an absolute risk reduction (AAR) of disease progression in a subject. Specifically, the present disclosure provides, among other things, methods for determining AAR in a subject receiving androgen deprivation therapy (ADT) and radiotherapy (RT) compared to RT alone where the absolute risk reduction is a measure of the likelihood of metastasis.

• 출원번호 : US2024/030876
• 출원인 : MYRIAD GENETICS, INC.
• 특허번호 :
• IPC : G16B-020/00(2019.01);C12Q-001/6886(2018.01);

The present invention belongs to the technical field of human body detection, and in particular relates to a passive human body detection method and apparatus, and a device and a medium, which are used for solving the problem of existing human body detection technology being easily interfered with and having low detection accuracy. The method comprises: acquiring an infrared thermal radiation signal in an environment, so as to acquire the temperature of a body to be detected; transmitting an electromagnetic wave to the environment and acquiring an echo signal that is reflected back; according to the echo signal, determining the position of said body in the environment; matching a threshold range according to the position of said body; and comparing the temperature of said body with the threshold range, so as to determine human body detection information in the environment. In the present invention, whether there is a person in the current environment is detected by combining electromagnetic wave detection and thermal imaging; and an interference signal can be effectively filtered, thereby greatly improving the accuracy and sensitivity of human body presence detection.

• 출원번호 : CN2024/094611
• 출원인 : BEIJING XSMART CENTURY TECHNOLOGY CO., LTD.
• 특허번호 :
• IPC : G01V-009/00(2006.01);G01V-003/00(2006.01);

The present invention relates to an electropneumatic solenoid valve for a pneumatically operated field device, in particular actuator, of a process engineering plant, such as a chemical plant, a petrochemical plant, a food-processing plant, such as a brewery, a nuclear power station or the like, comprising an air supply duct, an air discharge duct and a valve member mounted movably along an axial actuating direction, such as an impact valve member, in particular a magnetizable impact plate, which can take up an opening state, in which an actuating flow is permitted between the air supply duct and the air discharge duct, and a closing state, wherein, in the closing date, a pressure relief flow is permitted from the air supply duct into the air discharge duct.

• 출원번호 : EP2024/064044
• 출원인 : SAMSON AKTIENGESELLSCHAFT
• 특허번호 :
• IPC : F16K-001/36(2006.01);F16K-001/42(2006.01);F16K-031/06(2006.01);F16K-039/02(2006.01);

The present invention relates to a process for shaping keratin fibres, notably the hair, comprising steps with the aim of subjecting a tensioned lock of hair to illumination: exposing said keratin fibres to light radiation having an emission maximum in a wavelength range of between 280 nm and 650 nm, the process being characterized in that the keratin fibres to be treated receive an irradiance of greater than or equal to 1 W/cm and less than or equal to 50 W/cm2.

• 출원번호 : EP2024/064043
• 출원인 : L'OREAL
• 특허번호 :
• IPC : A45D-002/00(2006.01);A45D-007/00(2006.01);