The invention relates to biosensors and three-dimensional electrodes, which can be used for manufacturing electrochemical biosensors. The claimed process for obtaining of a three-dimensional electrode comprising the steps of: (i) providing a solid silicone-based formative bed, defining the three-dimensional electrode dimensions; (ii) introducing a UV curable polymer into the formative bed; (iii) positioning a mask over the formative bed filled with the UV curable polymer; wherein the mask comprises predefined patterns corresponding to a lattice structure, the patterns having areas that are transparent to UV light to define cells and supporting pillars of the lattice, and areas that are non-transparent to UV light to block UV exposure; (iv) exposing the UV curable polymer to UV light through the mask at a defined optical angle, such that the angled UV light exposure through the transparent areas of the mask defines the formation of cells and leaning supporting pillars of the lattice, while the areas of the mask that are non-transparent to UV light block the UV exposure; (v) removing the uncured portions of the UV curable polymer by a solvent, thereby revealing the three-dimensional lattice structure comprising cells and supporting pillars; (vi) subjecting the element obtained at a previous step to a treatment selected from thermal, chemical, physical, or radiation-based methods to impart a hydrophilic surface characteristic to the element; (vii) depositing a conductive layer onto the element's three-dimensional lattice structure, via an electroless plating by a deposition of at least 50 nm of a base or noble metal or metal alloy via reduction of metal ions in presence of a reducing agent.

• 출원번호 : LV2024/050013
• 출원인 : LATVIJAS UNIVERSITATES CIETVIELU FIZIKAS INSTITUTS
• 특허번호 :
• IPC : G01N-027/327(2006.01);G01N-033/53(2006.01);G03F-007/00(2006.01);G03F-007/20(2006.01);

The invention relates to an adjustment method (10) for adjusting a beam caustic (12), in particular a focal position (18), of a laser beam (14) of a laser beam unit (22) having an optical device (52), in particular for generating extreme ultraviolet radiation (EUV), comprising the method steps of: a) ascertaining (24) three beam diameters (26, 32, 36, 40) of the laser beam (14) at three measurement planes (28, 30, 34, 38) positioned along the laser beam propagation direction (16); b) determining (42) the beam caustic (12) of the laser beam (14) by analytically calculating beam propagation parameters of the laser beam (14) on the basis of the three ascertained beam diameters (26, 32, 36, 40); c) ascertaining (46) a laser beam deviation by comparing the beam caustic (12) with a target beam caustic (48) of the laser beam (14); d) adjusting (50) the laser beam unit (22), in particular the optical device (52), according to the ascertained laser beam deviation. The invention also relates to an adjustment system (58) and to a laser beam unit (22).

• 출원번호 : EP2024/078574
• 출원인 : TRUMPF LASERSYSTEMS FOR SEMICONDUCTOR MANUFACTURING SE
• 특허번호 :
• IPC : G01J-001/42(2006.01);G01J-001/02(2006.01);G01J-001/30(2006.01);H01S-003/00(2006.01);

Provided herein are combination therapy methods, compositions and uses involving adoptive T cell therapies, such as tumor infiltrating lymphocyte (TIL) therapies and low dose radiation therapy (LDRT). In some embodiments, the combination therapy methods, composition and uses also involve a chemotherapeutic regimen and/or a checkpoint inhibitor.

• 출원번호 : US2024/050815
• 출원인 : TURNSTONE BIOLOGICS CORP.
• 특허번호 :
• IPC : A61K-031/00(2006.01);A61K-035/17(2025.01);A61K-038/20(2006.01);A61K-039/00(2006.01);A61N-005/00(2006.01);A61P-035/00(2006.01);C07K-016/00(2006.01);

This disclosure relates to methods and systems for determining epigenetic states resulting from epigenetic modifying processes, particularly by use of molecules dynamics and models of epigenetic modifying processes.

• 출원번호 : US2024/050764
• 출원인 : ALTOS LABS, INC.
• 특허번호 :
• IPC : G16B-030/00(2019.01);G06N-003/08(2023.01);G06N-003/0985(2023.01);G16B-040/30(2019.01);G16B-020/00(2019.01);

According to an aspect, there is provided a waste storage cask for radioactive waste and method of loading said casks with waste. The cask including a main body, a cover, and removable overpack shielding configured to be removed after an amount of time has elapsed. The main body and the removable overpack shielding together attenuate radiation emitted from the radioactive waste below a threshold when the radioactive waste is freshly sealed in the cask. The main body attenuates radiation emitted from the radioactive waste below the threshold after the amount of time has elapsed. According to an aspect, there is provided a waste storage cask for radioactive waste. The cask including a main body, a cover, and a cap. The main body and the cover couple to form at least one primary seal. The main body and the cap couple to form at least two secondary seals.

• 출원번호 : CA2024/051337
• 출원인 : CANDU ENERGY INC.
• 특허번호 :
• IPC : G21F-005/06(2006.01);G21F-005/005(2006.01);G21F-005/12(2006.01);

According to the invention there is a method of applying a catalyst layer to a surface, the method comprising the steps of: providing a donor substrate having opposing first and second surfaces and providing a catalyst ink disposed as a layer on the second surface, wherein the catalyst ink comprises a catalyst and a solvent; providing an acceptor substrate, wherein the second surface of the donor substrate faces towards the acceptor substrate; and irradiating the catalyst ink with laser radiation at a wavelength which is absorbed by the catalyst ink so as to transfer the catalyst ink from the donor substrate to the acceptor substrate.

• 출원번호 : 24205639.8
• 출원인 : Johnson Matthey Public Limited Company
• 특허번호 :
• IPC : B01J-037/34(2006.01);H01M-008/0612(2016.01);C23C-014/04(2006.01);

PROBLEM TO BE SOLVED: To provide body temperature regulating clothing capable of efficiently, locally cooling or warming only desired specific parts of a body.SOLUTION: A temperature regulating vest being the body temperature regulating clothing, configured to attach Peltier element units 40 each including a cooling surface for absorbing heat and a heat-generating surface for generating heat, to a fabric 11 of a vest body 10, comprises: element attaching parts 20 to which the Peltier element units 40 can be attached and which are disposed at a plurality of sites on a back fabric 11B, where a heat radiation surface being any one face of the cooling surface or the heat-generating surface of the three Peltier element units 40 is attached to specific element attaching parts selected from the plurality of sites, with the surface facing and coming into contact with a body surface of a wearer, and has a control part capable of controlling the Peltier element units 40. The control part is electrically connected to each of the Peltier element units 40 by branch lines 56A, 56B and 56C divided and extending from a main line 56 that is collected in one line.SELECTED DRAWING: Figure 1

• 출원번호 : 2024177213
• 출원인 : LIBRE INC
• 특허번호 :
• IPC : A41D-013/005(2006.01)

Bioprocess bags are provided which retain good mechanical characteristics after radiation sterilization. The bags are constructed from a copolymer of tetrafluoroethylene. The tetrafluoroethylene is polymerized with at least one monomer selected from the group consisting of: ethylene; chlorotrifluoroethylene; vinyl fluoride; hexafluoropropylene; hexafluoroisobutene; monomers represented by CH═CX(CF)X (wherein X is H or F, X is H, F, or Cl, and n is an integer of 1 to 20); perfluoro(alkyl vinyl ethers) represented by CF═CF—ORf (wherein Rf is a C1-C20 perfluoroalkyl group or a C1-C17 perfluoroalkoxy alkyl group); and alkyl perfluorovinyl ether derivatives represented by CF═CF-OCH—Rf (wherein Rf is a C1-C5 perfluoroalkyl group). A particular version is polymerized with ethylene and CH═CX(CF)X (wherein X is H or F, X is H, F, or Cl, and n is an integer of 1 to 20). Various versions of the bag have high resistance to repeated bending, folding, and creasing; low water vapor transmissibility; high puncture resistance; high biocompatibility; and low reactivity. This makes them suitable for storing biomaterials and medical materials.

• 출원번호 : IB2024/059856
• 출원인 : DAIKIN AMERICA, INC.;DAIKIN INDUSTRIES, LTD.;
• 특허번호 :
• IPC : B65D-030/02(2006.01)

The present disclosure relates to a model training method, an image reconstruction method, and a related device. A computer device acquires a pre-trained target neural network model, the target neural network model being obtained by training a plurality of groups of training samples by means of a machine learning algorithm, and each group of training samples comprising a CTP image and a CTA image which are paired with each other, wherein the CTP image and the CTA image which are paired with each other correspond to the same selected level of target tissue; a target CTP image is input into the target neural network model, such that the target neural network model reconstructs a target CTA image on the basis of the target CTP image. The blood vessel imaging effect of the target CTA image is close to that of a real CTA image or is even better that that of the real CTA image, thereby providing a real and accurate reference basis for examination of each tissue and organ, and a patient can undergo one less CTA examination, thereby increasing the speed of one-stop CT examination for stroke, avoiding exposure to radiation of one more CTA examination, and reducing one injection of a contrast agent, lowering the risk of side effects generated by the contrast agent.

• 출원번호 : CN2024/123757
• 출원인 : SHANGHAI RADIODYNAMIC HEALTHCARE TECHNOLOGY CO., LTD.
• 특허번호 :
• IPC : G06T-011/00(2006.01);G06N-020/00(2019.01);

An antenna structure, a detection apparatus, and a terminal device, relating to the technical field of millimetre-wave radars, and used for reducing the profile height of the antenna structure. The antenna structure comprises a radome and an antenna. A first surface of the radome is in contact with a first surface of the antenna. The first surface of the antenna is provided with a radiation part, the first surface of the radome is provided with a first slot, and the first slot and the radiation part form a first cavity. The radome is attached on the antenna, and the slot is arranged in the radome at a position corresponding to the radiation part of the antenna. Therefore, an air gap between the radome and the antenna is saved, and the profile height of the antenna structure is reduced, so that the antenna structure can be applicable to an application scenario having a narrow installation space. Moreover, the slot in the radome ensures that an air gap exists between the radiation part of the antenna and the radome, thereby maintaining radiation performance of the antenna.

• 출원번호 : CN2024/123672
• 출원인 : SHENZHEN YINWANG INTELLIGENT TECHNOLOGIES CO., LTD.
• 특허번호 :
• IPC : H01Q-001/36(2006.01)