In one aspect, a method of imaging a biological specimen is disclosed, which includes defining a plurality of reference location points across a surface of the biological specimen, directing ablating radiation to the biological specimen at a first plurality of sample locations corresponding to a first subset of the defined reference location points to ablate at least a portion of the specimen at each of said locations, thereby generating a gas phase sample from each of said sample locations, ionizing each of the gas phase samples to generate ions corresponding to that gas phase sample, acquiring one or more mass signals corresponding to ions associated with each of the ablated portions, and identifying at least one region of interest based on analysis of the mass signals. An image of the identified region of interest can be acquiring using image mass cytometry.
- 출원번호 : IB2024/055307
- 출원인 : STANDARD BIOTOOLS CANADA INC.
- 특허번호 :
- IPC : H01J-049/26(2006.01);G02B-021/36(2006.01);