| 764418 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
608 Synergistic effect of the combination of ATG-017, an ERK1/2 inhibitor, and immune checkpoint inhibitor in preclinical cancer models |
2021-11-01 |
10.1136/jitc-2021-sitc2021.608 |
Chen Peng, Liu Yun, Deng Min, Wang Jian, Hoenemann Dirk, Lynch Kevin, Mei Jay, Shan Bo, Hou Bing |
| 764417 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
607 Regional delivery of a TLR9 agonist to boost checkpoint inhibitor responsiveness in liver metastases |
2021-11-01 |
10.1136/jitc-2021-sitc2021.607 |
Ghosh Chandra, O’Connell Kyle, Heatherton Kara, Laporte Jason, Guha Prajna, Cox Bryan, Katz Steven, Katz Steven |
| 764416 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
606 SAR444245 (THOR-707), an engineered non-alpha IL-2, enhances NK mediated antibody-dependent cellular cytotoxicity |
2021-11-01 |
10.1136/jitc-2021-sitc2021.606 |
Gavigan Julie-Ann, Acuff Nicole, Buetz Christen, Lampa Michael, Shi Chaomei, Zhang Yu-an, Chen Liqing, Balko Kelly, Cortez-Retamozo Virna, Mooney Jill, Caffaro Carolina, Milla Marcos, Theilhaber Joachim, Jackson Donald, Wagenaar Timothy, Abbadessa Giovanni, Shaffer Donald, Li Xiangming |
| 764415 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
411 INNATE: immunotherapy during neoadjuvant therapy for rectal cancer to elucidate local and systemic therapeutic responses |
2021-11-01 |
10.1136/jitc-2021-sitc2021.411 |
Sanford Nina, Elghonaimy Eslam, Kardosh Adel, Kazmi Syed, Pogacnik Javier Salgado, Yang Xiaodong, Timmerman Robert, Aguilera Todd |
| 764414 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
410 Phase I interim study results of Nous-209, an off-the-shelf immunotherapy, with pembrolizumab, for the treatment of tumors with a deficiency in mismatch repair/microsatellite instability (dMMR/MSI) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.410 |
Overman Michael, Fakih Marwan, Le Dung, Shields Anthony, Pedersen Katrina, Shah Manish, Mukherjee Sarbajit, Faivre Thea, Leoni Guido, D’Alise Anna Morena, Cotugno Gabriella, Langone Francesca, Capone Stefania, Sorbo Maria Rosaria Del, Scarselli Elisa, Delaite Patricia |
| 764413 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
407 A phase 1b KEYNOTE-B79 trial evaluating non-gene edited allogeneic CAR T-cells, CYAD-101, post FOLFOX preconditioning, followed by pembrolizumab, in refractory metastatic colorectal cancer patients |
2021-11-01 |
10.1136/jitc-2021-sitc2021.407 |
Flament Anne, Lehmann Frédéric, Alcantar-Orozco Erik, Cerf Emilie, Lonez Caroline, Gilham David, Morris Charles |
| 764412 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
310 T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade |
2021-11-01 |
10.1136/jitc-2021-sitc2021.310 |
Muroyama Yuki, Manne Sasikanth, Greenplate Allison, Mathew Divij, Oldridge Derek, Chilukuri Lakshmi, Xu Caiyue, Herati Ramin, Huang Alexander, Zamarin Dimitriy, Friedman Claire, John Wherry E |
| 764411 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
308 Transcriptomic analysis of melanoma patients in adjuvant setting treated with anti PD1 therapy: real life study |
2021-11-01 |
10.1136/jitc-2021-sitc2021.308 |
Mallardo Domenico, Trojaniello Claudia, Vitale Maria Grazia, d’angelo grazia, White Andrew, Capone Mariaelena, Sorrentino Antonio, Madonna Gabriele, Tuffanelli Marilena, Vanella Vito, Festino Lucia, Simeone Ester, Caracò Corrado, Normanno Nicola, Warren Sarah, Ascierto Paolo |
| 764410 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
293 Distinct tumor infiltrating treg lineages are associated with response to anti-PD1 checkpoint blockade in non-small cell lung cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.293 |
Dykema Arbor, Zhang Boyang, Zhang Jiajia, Ji Zhicheng, Li Taibo, Burman Poromendro, Caushi Justina, Ji Hongkai, Pardoll Andrew, Smith Kellie |
| 764409 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
283 TIM-3 blockade modulates the tumor microenvironment improving the outcome of preclinical pediatric diffuse midline glioma models |
2021-11-01 |
10.1136/jitc-2021-sitc2021.283 |
Ausejo-Mauleon Iker, Labiano Sara, Laspidea Virginia, Garcia-Moure Marc, Nava Daniel de la, Becher Oren, Filbin Mariella, Pastor Fernando, Alonso Marta |
