| 764448 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
284 Integrated molecular characterization of primary resistance mechanisms to immune checkpoint blockade in advanced non-small cell lung carcinoma (a-NSCLC) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.284 |
Besse Benjamin, Colette DIB, Marquez Eladio, Lee Joon Sang, Yan Shu, Chiron Marielle, Combeau Cecile, Biancotto Angelique, Blanc-Durand Félix, Aldea Mihaela, Planchard David, Scoazec Jean-Yves, Lacroix Ludovic, Rouleau Etienne, Chaput-Gras Nathalie, Rafie Saloomeh, Marabelle Aurélien, Angevin Eric, Pollard Jack |
| 764447 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
281 Measuring immune checkpoint inhibitor efficacy using primary patient-derived 3D spheroids |
2021-11-01 |
10.1136/jitc-2021-sitc2021.281 |
Appleton Kathryn, Lassahn Katy, Elrod Ashley, DesRochers Tessa |
| 764446 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
280 Clinical outcomes of immunotherapy continued beyond radiographic progression in older adults with advanced non-small cell lung cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.280 |
Singhi Eric, Mott Frank, Worst Michelle, Leung Cheuk Hong, Lee Jack, Carter Brett, Presley Carolyn, Lewis Jeff, Rinsurongkawong Waree, Rinsurongkawong Vadeerat, Zhang Jianjun, Gibbons Don, Vaporciyan Ara, Heymach John, Altan Mehmet |
| 764445 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
278 Systematic review and meta-analysis evaluating the impact of antibiotic use on clinical outcomes of non-small-cell lung cancer patients treated with immune checkpoint inhibitors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.278 |
Crespin Athéna, Bandinelli Pierre-Alain, Bescop Clément Le, Buffet Renaud, Gunzburg Jean De, Vitry Fabien, Zalcman Gérard, Cervesi Julie |
| 764444 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
276 Discovery and preclinical characterization of anti-LILRB2 antibodies that rescue T cells from macrophage-mediated immune suppression |
2021-11-01 |
10.1136/jitc-2021-sitc2021.276 |
Zuck Meghan, Dinh Huyen, Wall Valerie, Lam Sam, Chandrasekaran Ramya, Zapata Francisco, Loh Texia, Loh Lauren, Bouchlaka Myriam, Graddis Tom, Zuck Meghan, Puri Kamal, Probst Peter |
| 764443 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
274 CD47 x EpCAM bispecific antibody represents a novel approach for treating EpCAM overexpressing solid tumors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.274 |
Wang Xinhua, Wong Oi Kwan, Shi Lei, Fei Qi, Post Leonard, Chen Xiaocheng |
| 764442 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
273 Application of pharmacokinetic-pharmacodynamic modeling to select the optimal dose of ALX148, a CD47 blocker |
2021-11-01 |
10.1136/jitc-2021-sitc2021.273 |
Demin Oleg, Vasileva Elena |
| 764441 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
272 A novel bispecific macrophage engager antibody (BiME) designed for cancer immunotherapy |
2021-11-01 |
10.1136/jitc-2021-sitc2021.272 |
Lu Hongtao, Sun Dawei, Niu Xiaofeng, Geng Yanan, Wang Jing, Jiang Haixia, Gao Rui, Wu Zhihao, Qiu Yangsheng |
| 764440 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
271 Development of OR2805, an anti-CD163 antibody derived from an elite responder to checkpoint inhibitor therapy that relieves immunosuppression caused by M2c macrophages |
2021-11-01 |
10.1136/jitc-2021-sitc2021.271 |
Probst Peter, Simmons Randi, Dinh Huyen, Zuck Meghan, Wall Valerie, Bouchlaka Myriam, Lam Sam, Fox Ray, Whitman Darbie, Graddis Tom, Puri Kamal |
| 764439 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
67 Cancer aneuploidy is associated with a distinct tumor immune microenvironment and impacts outcomes to immune checkpoint inhibition in nonsquamous non-small cell lung cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.067 |
Alessi Joao Victor, Ricciuti Biagio, Lin-Liu Yvonne, Gupta Hersh, Wang Xinan, Lamberti Giuseppe, Recondo Gonzalo, Vaz Victor, Barrichello Adriana, Nishino Mizuki, Cherniack Andrew, Lindsay James, Sharma Bijaya, Pfaff Kathleen, Felt Kristen, Rodig Scott, Awad Mark |
