| 764158 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
702 TJ-CD4B (ABL111), a Claudin18.2-targeted 4-1BB tumor engager induces potent tumor-dependent immune response without dose-limiting toxicity in preclinical studies |
2021-11-01 |
10.1136/jitc-2021-sitc2021.702 |
Jiang Wenqing, Wang Zhengyi, Sheng Zhen, Jung Jaeho, Guo Taylor |
| 764157 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
701 Activating CD73 on B cells as a target for immunotherapy of COVID-19 and viral associated cancers: clinical activity in human papilloma virus positive (HPV) head and neck squamous cell cancers (HNSCC) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.701 |
Luke Jason, Merchan Jaime, Hughes Brett, Sosman Jeffrey, Tripathi Abhishek, Puzanov Igor, Marron Thomas, Marrone Kristen, Hill Craig, Janc James, Rudnick Jenny, Hu Shenshen, Mobasher Mehrdad, Mahabhashyam Suresh, Miller Richard |
| 764156 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
700 Increasing MHC-I expression to potentiate immune checkpoint blockade therapy |
2021-11-01 |
10.1136/jitc-2021-sitc2021.700 |
Gu Shengqing, Zhang Wubing, Wang Xiaoqing, Jiang Peng, Traugh Nicole, Li Ziyi, Meyer Clifford, Stewig Blair, Xie Yingtian, Bu Xia, Manos Michael, Font-Tello Alba, Gjini Evisa, Lako Ana, Lim Klothilda, Conway Jake, Tewari Alok, Zeng Zexian, Sahu Avinash Das, Tokheim Collin, Weirather Jason, Fu Jingxin, Zhang Yi, Kroger Benjamin, Liang Jin Hua, Cejas Paloma, Freeman Gordon, Rodig Scott, Long Henry, Gewurz Benjamin, Stephen Hodi F., Brown Myles, Shirley Liu X |
| 764155 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
699 ATYR2810 an anti-NRP2 monoclonal antibody targets tumor-associated macrophages |
2021-11-01 |
10.1136/jitc-2021-sitc2021.699 |
Tyler Samantha, Ferrer Michaela, Escobedo Erik, Rauch Kaitlyn, Klopp-Savino Sofia, Rahman Justin, Xu Zhiwen, Chong Esther, Paz Suzanne, Nangle Leslie |
| 764154 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
697 Telomerase-driven telomeric DNA modification in cancer cells leads to efficient induction of cGAS-mediated innate and adoptive immune responses |
2021-11-01 |
10.1136/jitc-2021-sitc2021.697 |
Obrocea Mihail, Shay Jerry, Gryaznov Sergei, Mender Ilgen, Siteni Silvia, Vitoc Vlad |
| 764153 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
696 Single-cell RNA-seq reveals the critical roles of the STING- and MDA5-mediated cytosolic nucleic acid-sensing pathways as well as IFNAR/STAT2 signaling in recombinant MVA-induced antitumor immunity |
2021-11-01 |
10.1136/jitc-2021-sitc2021.696 |
Liu Shuaitong, Mazo Gregory, Zhang Tuo, Yang Ning, Wang Yi, Tan Adrian, Wang Jiahu, Choi John, Xiang Jenny Zhaoying, Merghoub Taha, Wolchok Jedd, Deng Liang |
| 764152 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
693 Mucosal-associated invariant T (MAIT) cell regulation networks in anti-tumor immunity |
2021-11-01 |
10.1136/jitc-2021-sitc2021.693 |
Ruf Benjamin, Catania Vanessa, Kedei Noemi, Wabitsch Simon, Ma Chi, Diggs Laurence, Zhang Qianfei, Heinrich Bernd, Subramanyam Varun, Cui Linda, Sakai Shunsuke, Oh Sangmi, Stovroff Merrill, Barry Clifton, Barber Daniel, Kroemer Alexander, Korangy Firouzeh, Greten Tim |
| 764151 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
535 A phase I/II study of REGN7075 (EGFRxCD28 costimulatory bispecific antibody) in combination with cemiplimab (anti–PD-1) in patients with advanced solid tumors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.535 |
Lakhani Nehal, Johnson Melissa, Groisberg Roman, Han Hyunsil, Casey Kerry, Li Siyu, Skokos Dimitris, Seebach Frank, Lowy Israel, Fury Matthew, Mathias Melissa |
| 764150 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
532 First-in-human phase 1 trial of SRK-181: a latent TGFβ1 inhibitor, alone or in combination with anti-PD-(L)1 treatment in patients with advanced solid tumors (DRAGON trial) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.532 |
Yap Timothy, Barve Minal, Gainor Justin, Bockorny Bruno, Ju Yawen, Cote Shaun, Bilic Sanela, Liu Lan, Chyung Yung, Legler Michelle, Gan Lu, McKean Meredith |
| 764149 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
531 A Phase 1b multi-tumor cohort study of cabozantinib plus atezolizumab in advanced solid tumors: results of the triple-negative breast cancer, ovarian cancer, and endometrial cancer cohorts |
2021-11-01 |
10.1136/jitc-2021-sitc2021.531 |
Winer Ira, Wimalasingham Akhila, Baranda Joaquina, Santoro Armando, Spencer Kristen, Baldini Capucine, Duska Linda, Subbiah Vivek, Patel Sandip, Khrizman Polina, Lancker Griet Van, Andrianova Lana, Atwal Sumandeep, Sharma Keerti, Manso Luis |
