| 764138 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
924 The spatial hierarchy of primary and recurrent medulloblastoma tumor ecosystems |
2021-11-01 |
10.1136/jitc-2021-sitc2021.924 |
Donovan Laura, Hopkins Bei, Draper Ben, Shah Rivani, Roman Kristin, Remeniuk Bethany |
| 764137 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
923 Hedgehog signaling drives epithelial-to-mesenchymal transition, immune evasion, and anti-PD-1 resistance through coordinated upregulation of Wnt ligands and PGE2 synthesis |
2021-11-01 |
10.1136/jitc-2021-sitc2021.923 |
DeVito Nicholas, Sturdivant Michael, Theivanthiran Balamayooran, Nguyen Y-Van, Plebanek Michael, Hanks Brent |
| 764136 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
922 A novel autotaxin inhibitor, IOA-289, modulates tumor, immune and stromal cell function and has monotherapy activity in fibrotic cancer models |
2021-11-01 |
10.1136/jitc-2021-sitc2021.922 |
Deken Marcel, Niewola Karolina, Matas-Rico Elisa, Medhi Ragini, Carruthers Alan, Cheasty Anne, Peyruchaud Olivier, Fraser Amy, Shah Pritom, Moolenaar Wouter, Veen Lars van der, Lahn Michael, Johnson Zoe |
| 764135 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
295 Tumor cell- intrinsic expression of FGFR3 drives anti-PDL-1 immunotherapy resistance in a murine bladder cancer model |
2021-11-01 |
10.1136/jitc-2021-sitc2021.295 |
Fleming-Trujillo Erica, Bloodworth Jeffrey, Fernald Anthony, Ramsland Aubrianna, Gajewski Thomas, Sweis Randy |
| 764134 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
335 Leukaphereses to obtain monocytes to produce dendritic cells in manufacturing of personal autologous AV-GBM-1 vaccines in a phase II trial in patients with newly diagnosed glioblastoma |
2021-11-01 |
10.1136/jitc-2021-sitc2021.335 |
LaRocca Renato, Bota Daniela, Piccione David, Duma Christopher, Kesari Santosh, Carrillo Jose, Kong Xiang-Tang, Hsu Frank, Aiken Robert, Abedi Mehrdad, Taylor Thomas, Hsieh Candace, Nistor Gabriel, Dillman Robert |
| 764133 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
187 Multi-omic single-cell profiling demonstrates that competition for fatty acids and fatty acid oxidation enables tumor-infiltrating lymphocyte function and survival |
2021-11-01 |
10.1136/jitc-2021-sitc2021.187 |
Paniagua Melisa Angela, Haymaker Cara, Adolacion Jay R, An Xingyue, Creasy Caitlin, Fathi Mohsen, Rezvan Ali, Geiger Tamar, Harel Michal, Robinson Jonathan, Amritkar Amit, Woodman Scott, Hwu Patrick, Bernatchez Chantale, Varadarajan Navin |
| 764132 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
392 A phase 1a/b study of IK-175, an oral AHR inhibitor, alone and in combination with nivolumab in patients with locally dvanced or metastatic solid tumors and urothelial carcinoma |
2021-11-01 |
10.1136/jitc-2021-sitc2021.392 |
McKean Meredith, Luke Jason, Lakhani Nehal, Bashir Babar, Aggen David, Tan Alan, Kacena Katherine, Wang Lei, Timothy Marissa, Santillana Sergio |
| 764131 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
231 Molecular insights on safety and anti-tumor activity of a non-irAE-inducing anti-CTLA-4 monoclonal antibody ONC-392 |
2021-11-01 |
10.1136/jitc-2021-sitc2021.231 |
Liu Yang, Zhang Yan, Du Xuexiang, Liu Mingyue, Fang Xianfeng, Mu Libing, Tevetnitsky Vadim, Devenport Martin, Zheng Pan |
| 764130 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
229 CX3CR1 in exhausted CD8 T cell states |
2021-11-01 |
10.1136/jitc-2021-sitc2021.229 |
Chaudhri Apoorvi, Wang Yunfei, Hung Shao-Hsi, Lizee Gregory, Andrian Ulrich Von, Hwu Patrick, Freeman Gordon |
| 764129 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
903 Human cancer-associated fibroblast subsets can predict immune checkpoint response in head and neck cancer patients |
2021-11-01 |
10.1136/jitc-2021-sitc2021.903 |
Graves Diana, Obradovic Aleksandar, Korrer Michael, Wang Yu, Roy Sohini, Xu Yaomin, Luginbuhl Adam, Curry Joseph, Gibson Michael, Hurley Paula, Uppaluri Ravindra, Drake Charles, Califano Andrea, Kim Young |
