| 764368 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
251 The use of small molecule inhibitors to target novel pathways in exhausted T cells for immuno-oncology therapeutic intervention |
2021-11-01 |
10.1136/jitc-2021-sitc2021.251 |
Acklam Francis, Hay Joanne, Turner Darryl, Barbour Mark, Singh Preeti, Grant Courtney, Gooding Hayley, Rzepecka Justyna, McPherson Rhoanne |
| 764367 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
250 Spatial-transcriptomic analysis of tumor-immune microenvironment in AML patients receiving pembrolizumab and decitabine |
2021-11-01 |
10.1136/jitc-2021-sitc2021.250 |
Zhao Chen, Wong-Rolle Abigail, Divakar Prajan, Calvo Katherine, Hourigan Christopher |
| 764366 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
246 Effectiveness and utilization of first-line immune checkpoint inhibitors for patients with extracranial & intracranial metastatic melanoma |
2021-11-01 |
10.1136/jitc-2021-sitc2021.246 |
Lamba Nayan, Iorgulescu Bryan |
| 764365 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
398 neoIRX: a phase II trial of locoregional cytokine therapy to promote immunologic priming and clinical response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.398 |
Sanchez Katherine, Conlin Alison, Peddi Parvin, Stanton Sasha, Ruzich Janet, Perlewitz Kelly, Wu Yaping, Moxon Nicole, Mellinger Staci, Sun Zhaoyu, Redmond William, Page David |
| 764364 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
383 Durable responses with intratumoral electroporation of plasmid interleukin 12 plus pembrolizumab in patients with advanced melanoma progressing on an anti-PD-1 antibody: updated data from keynote 695 |
2021-11-01 |
10.1136/jitc-2021-sitc2021.383 |
Fernandez-Penas Pablo, Carlino Matteo, Tsai Katy, Atkinson Victoria, Shaheen Monaster, Thomas Sajeve, Mihalcioiu Catalin, Hagen Tom Van, Roberts-Thomson Rachel, Haydon Andrew, Mant Andrew, Butler Marcus, Daniels Gregory, Bunchbinder Elizabeth, Hyngstrom John, Moller Mecker, Puzanov Igor, Lance Cowey C, Whitman Eric, Ballesteros-Merino Carmen, Jensen Shawn, Fox Bernard, Schmidt Emmett, Diede Scott, Setta Rebecca, Sell Jendy, Canton David, Aung Sandra, Twitty Christopher, Xie Sunny, Lu Ying, O’Keefe Bridget, Algazi Alain, Daud Adil |
| 764363 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
268 KVA 12.1 a novel fully human anti-VISTA antibody: clinical trial design in monotherapy and in combination with an anti-PD1 antibody |
2021-11-01 |
10.1136/jitc-2021-sitc2021.268 |
Guillaudeux Thierry, Iadonato Shawn, Tarcha Eric, Philips Craig |
| 764362 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
263 ASD141, an innate checkpoint inhibitor, modulates tumor associated myeloid cells through CD11b and enhances current immune checkpoint blockade in preclinical model |
2021-11-01 |
10.1136/jitc-2021-sitc2021.263 |
Chang Chia-Ming, Huang Jason (Ping-Yen), Tsai I-Fang, Lu Yen-Ta |
| 764361 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
260 CD47 antibody, AO-176 demonstrates potent anti-tumor activity in pre-clinical solid tumor xenografts as a single agent and in combination with multiple classes of therapeutics |
2021-11-01 |
10.1136/jitc-2021-sitc2021.260 |
Andrejeva Gabriela, Capoccia Benjamin, Delston Rachel, Donio Michael, Hiebsch Ronald, Puro Robyn, Wilson Casey, Kashyap Arun, Pereira Daniel |
| 764360 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
351 KEYNOTE-365 cohort D: pembrolizumab plus abiraterone acetate and prednisone in patients with chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.351 |
Piulats Josep, Ferrario Cristiano, Linch Mark, Stoeckle Michael, Laguerre Brigitte, Arranz Jose, Todenhoefer Tilman, Fong Peter, Berry William, Emmenegger Urban, Mourey Loic, Mar Nataliya, Appleman Leonard, Joshua Anthony, Conter Henry, Li Xin Tong, Schloss Charles, Poehlein Christian, Bono Johann De, Yu Evan |
| 764359 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
586 Monitoring the impact of MDSC targeting drugs in combination with nivolumab on activation and proliferation of tumor resident effector immune cells in patient-derived 3D-EXplore platform |
2021-11-01 |
10.1136/jitc-2021-sitc2021.586 |
Ehrhart Jared, Bunch Brittany, Sussman Kelly, Guzman Kelly, Altiok Soner |
