| 764218 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
951 A phase 1 first in human study of adenovirally transduced anti-HER2 CAR macrophages in subjects with HER2 overexpressing solid tumors: preliminary safety, pharmacokinetics, and TME reprogramming data |
2021-11-01 |
10.1136/jitc-2021-sitc2021.951 |
Reiss Kim, Yuan Yuan, Barton Debora, Ronczka Amy, Cushing Daniel, Klichinsky Michael, Abramson Sascha, Qureshi Rehman, Condamine Thomas, Dees Elizabeth |
| 764217 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
950 Final analysis: phase 1b study investigating intratumoral injection of toll-like receptor 9 agonist vidutolimod ± pembrolizumab in patients with PD-1 blockade–refractory melanoma |
2021-11-01 |
10.1136/jitc-2021-sitc2021.950 |
Kirkwood John, Zakharia Yousef, Davar Diwakar, Buchbinder Elizabeth, Medina Theresa, Daud Adil, Ribas Antoni, Chmielowski Bartosz, Niu Jiaxin, Gibney Geoffrey, Margolin Kim, Olszanski Anthony, Mehmi Inderjit, Sato Takami, Shaheen Montaser, Zhao Luping, Liu Hong, Kelley Heather, Weiner George, Luke Jason, Bobilev Dmitri, Krieg Arthur, Wooldridge James, Milhem Mohammed |
| 764216 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
949 First-in-human study of the first acid pH-sensitive and recycling CTLA-4 antibody that preserves the immune tolerance checkpoint to avoid immunotherapy-related adverse events in cancer patients |
2021-11-01 |
10.1136/jitc-2021-sitc2021.949 |
Li Tianhong, Tang Mei, Kelly Karen, Chen Hui Amy, Joo Stacy, Khan Imaan, Do Nicole, Touomou Raymond, Chen Dan, Liu Yang, Zheng Pan |
| 764215 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
948 Final results from AIPAC: A phase IIb comparing eftilagimod alpha (a soluble LAG-3 protein) vs. placebo in combination with weekly paclitaxel in HR+ HER2- MBC |
2021-11-01 |
10.1136/jitc-2021-sitc2021.948 |
Wildiers Hans, Dirix Luc, Armstrong Anne, Cuypere Eveline De, Dalenc Florence, Chan Steven, Marme Frederik, Schröder Carolina Pia, Huober Jens, Vuylsteke Peter, Jacquin Jean-Philippe, Brain Etienne, Kümmel Sherko, Pápai Zsuzsanna, Mueller Christian, Brignone Chrystelle, Triebel Frederic |
| 764214 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
947 Recombinant myxoma virus MC509-N1 demonstrates antitumor efficacy as monotherapy and in combination with immune checkpoint inhibitors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.947 |
Gansukh Enkhtaivan, Alain Tommy, Kim Tae-Geuk, Namgung Ye-Na, Son Ka-Yeon, Jeong Yeo-Jin, Lee Yeon-Sook |
| 764213 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
946 Standardized transcriptional profiling for optimizing cellular therapies: a multi-center PICI-NanoString collaboration |
2021-11-01 |
10.1136/jitc-2021-sitc2021.946 |
Church Sarah, Bailey Christina, Warren Sarah, Butterfield Lisa |
| 764212 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
945 Characterization of the immune landscape of malignant pleural effusion composition from patients with metastatic breast carcinoma: a pilot study |
2021-11-01 |
10.1136/jitc-2021-sitc2021.945 |
Laberiano Caddie Dy, Parra Edwin, Gan Qiong, Ibarguen Heladio, Zang Shanyu, Yoon Esther |
| 764211 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
944 Fibroblasts as paracrine targets of the oncometabolite D-2-HG in the IDH1-mutant cholangiocarcinoma tumor microenvironment |
2021-11-01 |
10.1136/jitc-2021-sitc2021.944 |
Zabransky Daniel, Jain Prerna, Mody Kabir, El-Refai Sherif, Jaffee Elizabeth, Yarchoan Mark |
| 764210 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
943 3D in vitro tumor model platform rapidly assays immunotherapy efficacy with high content imaging and downstream phenotypic changes with flow cytometry and cytokine analysis |
2021-11-01 |
10.1136/jitc-2021-sitc2021.943 |
Xue Bin, Schuler Julia, Harrod Christopher, Hribar Kolin |
| 764209 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
481 Phase 1/2 study of THOR-707 (SAR444245), a pegylated recombinant non-alpha IL-2, as monotherapy and in combination with pembrolizumab or cetuximab in patients (pts) with advanced solid tumors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.481 |
Falchook Gerald, Gan Hui, Fu Siqing, McKean Meredith, Azad Arun, Sommerhalder David, Wang Judy, Tan Tira, Chee Chen, Barve Minal, Lemeque charlotte, Acuff Nicole, Pham Helene, Mooney Jill, Wang Rui, Marina Neyssa, Abbadessa Giovanni, Meniawy Tarek |
