| 763928 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
884 Engineered toxin body mediated depletion of TIGIT expressing immune cells for cancer immunotherapy |
2021-11-01 |
10.1136/jitc-2021-sitc2021.884 |
Saputra Elizabeth, Cornelison Garrett, Mitchell Jennifer, Williams Karia, Mendiola Andrea, Orlandella Rachael, Majercak John, Dekker Joseph, Moore Chris, Khanna Swati |
| 763927 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
883 An anti-carcinoma monoclonal antibody (mAb) NEO-201 can also target human acute myeloid leukemia (AML) cell lines in vitro |
2021-11-01 |
10.1136/jitc-2021-sitc2021.883 |
Romano Alessandra, Parrinello Nunziatina, Marino Sara, Spina Enrico La, Fantini Massimo, Arlen Philip, Tsang Kwong, Raimondo Francesco Di |
| 763926 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
881 Enhanced antibody-mediated phagocytosis and antibody-mediated cell cytotoxicity using tetravalent, bispecific innate cell engagers (ICE®) in 3D spheroids |
2021-11-01 |
10.1136/jitc-2021-sitc2021.881 |
Pinto Sheena, Jackson Savannah, Knoch Julia, Breunig Christian, Schottelius Arndt, Koch Joachim |
| 763925 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
877 PSGL-1 blocking antibodies repolarize tumor associated macrophages, reduce suppressive myeloid populations and induce inflammation in the tumor microenvironment, leading to suppression of tumor growth |
2021-11-01 |
10.1136/jitc-2021-sitc2021.877 |
Nguyen Phuong, Ritter Jessica, Zafari Mohammad, Manfra Denise, Komoroski Veronica, O’Nuallain Brian, Phennicie Ryan, Kauffman Kevin, Nowakowska Dominika, Wahle Joe, Sazinsky Steve, Brehm Michael, Feldman Igor, Novobrantseva Tatiana |
| 763924 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
876 Intratumoral administration and local retention of IL-2/IL-12 fusion proteins drive a potent systemic anti-tumor immune response |
2021-11-01 |
10.1136/jitc-2021-sitc2021.876 |
Naveen Mehta, Li Bochong, Wittrup Dane, Baeuerle Patrick, Michaelson Jennifer |
| 763923 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
874 Development of BCA101, a bifunctional antibody capable of simultaneously disabling EGFR and TGFβ signaling, as novel single-agent immunotherapy |
2021-11-01 |
10.1136/jitc-2021-sitc2021.874 |
Boreddy Srinivas Reddy, Nair Reshmi, Banerjee Arindam, Kuriakose Anshu, Pandey Prashant Kumar, Dey Chaitali, Shri Meena, Rao Shruthi, Shivakumar Bhadravathi Marigowda, Kuriakose Moni Abhram, Reddy Ram Bhupal, Suresh Amritha, Moole Praveen Reddy, Bughani Usha, Tan Seng-Lai, Nair Pradip |
| 763922 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
873 S-531011, a novel anti-human CCR8 antibody: anti-tumor responses through depletion of tumor-infiltrating CCR8-positive Tregs |
2021-11-01 |
10.1136/jitc-2021-sitc2021.873 |
Nagai Ryohei, Nagira Morio, Nogami Wataru, Hirata Michinari, Ueyama Azumi, Yoshikawa Mai, Ohkura Naganari, Wada Hisashi, Nagira Yoji |
| 763921 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
872 PD1 x TGFbR2 and CD5 x TGFbR2 bispecifics selectively block TGFbR2 on target-positive T cells, promote T cell activation, and elicit an anti-tumor response in solid tumors |
2021-11-01 |
10.1136/jitc-2021-sitc2021.872 |
Moore Gregory, Schubbert Suzanne, Bonzon Christine, Avery Kendra, Rashid Rumana, Pong Erik, Ochyl Lukasz, Nisthal Alex, Chu Seung, Ernst James, Desjarlais John |
| 763920 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
405 Camrelizumab combined with paclitaxel and nedaplatin as neoadjuvant therapy for locally advanced esophageal squamous cell carcinoma (ESPRIT): a phase II, single-arm, exploratory research |
2021-11-01 |
10.1136/jitc-2021-sitc2021.405 |
Ma Jianqun, Zhang Jinfeng, Yang Yingnan, Zheng Dayong, Wang Xiaoyuan, Liang Hao, Zhang Luquan, Xin Yanzhong, Ling Xiaodong, Fang Chengyuan, Jiang Hao, Meng Hongxue, Zheng Wei |
| 763919 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
50 In-situ visualization and measurement of tumor-infiltrating lymphocytes (TILs) on intact FFPE renal cell carcinoma (RCC) tissue using the spatial molecular imager (SMI) |
2021-11-01 |
10.1136/jitc-2021-sitc2021.050 |
Newell Evan, Kim Youngmi, Ryu Heeju, Li Shamin, Leon Michael, Kim Sean, Gregory Mark, Danaher Patrick, Beechem Joseph |
