| 764078 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
878 Novel microbial immunotherapy approach for the treatment of bladder cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.878 |
Glanville Nicholas, Oke Tobi, Domingos-Pereira Sonia, Polak Lenka, Nardelli-Haefliger Denise, Deban Livija |
| 764077 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
875 AL009, a fusion protein and multi-Siglec inhibitor, repolarizes suppressive myeloid cells and potentiates anti-cancer effects |
2021-11-01 |
10.1136/jitc-2021-sitc2021.875 |
Nalle Sam, Lam Helen, Leung Ling, Liang Spencer, Maslyar Daniel |
| 764076 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
871 Construction and evaluation of interleukin 3 (IL3)-zetakine redirected cytolytic T Cells for the treatment of CD123 expressing acute myeloid leukemia |
2021-11-01 |
10.1136/jitc-2021-sitc2021.871 |
Moeller Rebecca, Scherer Julian, Kassim Sadik |
| 764075 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
870 Targeting GCN2 kinase-driven stress response inactivation to restore tumor immunity in metastatic triple negative breast cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.870 |
Vankayalapati Hariprasad, Medley Kyle, Li Zhaoliang, Yan Dongqing, Bearss David, Welm Alana |
| 764074 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
864 Identification of a novel allosteric oral Cbl-b inhibitor that augmented T cell response and enhanced NK cell killing in vitro and in vivo |
2021-11-01 |
10.1136/jitc-2021-sitc2021.864 |
Kuai Jun, Bi Yingzhi, Qi Yilin, Conrady Deborah, Govindaraj Rajiv, Hone Graham, Aldrin Denny R, Carson Ken, Harriman Geraldine, Wang Fang |
| 764073 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
863 In vitro and in vivo studies establish DuoBody®-CD3xB7H4 as a novel drug candidate for the treatment of solid cancers |
2021-11-01 |
10.1136/jitc-2021-sitc2021.863 |
Koopman Louise, Vries Laura Smits-de, Egerod Frederikke Lihme, Wubben Sebastiaan, Houtkamp Mischa, Poot Stefanie De, Paauwe Madelon, Brink Edward van den, Gorlani Andrea, Verzijl Dennis, Sasser Kate, Breij Esther |
| 764072 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
682 PKC agonism restricts innate immune suppression, promotes antigen cross-presentation and synergizes with agonistic CD40 therapy in breast cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.682 |
Chaib Mehdi, Makowski Liza, Yarbro John, Sipe Laura, Daria Deidre |
| 764071 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
681 An ex vivo 3D tumoroid model of fresh patient tissue (3D-EXplore) to assess the phagocytic activity of tumor resident innate immune cells |
2021-11-01 |
10.1136/jitc-2021-sitc2021.681 |
Guzman Kelly, McIntosh Olivia, Bunch Brittany, Yarinsky Jacob, Ehrhart Jared, Altiok Soner |
| 764070 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
679 Tumor hypoxia drives suppressor function in exhausted T cells limiting antitumor immunity |
2021-11-01 |
10.1136/jitc-2021-sitc2021.679 |
Vignali Paolo, DePeaux Kristin, Watson McLane, Scharping Nicole, Menk Ashley, Delgoffe Greg |
| 764069 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
678 The neonatal Fc receptor is elevated in monocyte-derived immune cells in pancreatic cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.678 |
Thomas Justin, Torok Molly, Agrawal Kriti, Vu Trang, Castillo Alyssa, Chen Min, Remaily Bryan, Kim Kyeongmin, Xie Zhiliang, Kulp Samuel, Owen Dwight, Phelps Mitch, Coss Christopher, Mace Thomas |
