| 764588 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
855 Development of a novel anti-multiple myeloma chimeric antigen receptor T cell therapy |
2021-11-01 |
10.1136/jitc-2021-sitc2021.855 |
Hay Chuck, Faber Mary, Adeyanju Kemi, Medin Jeffrey |
| 764587 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
852 Trifunctional NKp46/CD16a-NK cell engager targeting CD123 overcomes acute myeloid leukemia resistance to ADCC |
2021-11-01 |
10.1136/jitc-2021-sitc2021.852 |
Gauthier Laurent, Virone-Oddos Angela, Virone-Oddos Angela, Beninga Jochen, Rossi Benjamin, Nicolazzi Céline, Amara Céline, Blanchard-Alvarez Audrey, Gourdin Nicolas, Courta Jacqueline, Basset Alexandra, Guillot Franceline, Grondin Gwendoline, Bonnevaux Hélène, Bauchet Anne-Laure, Morel Ariane, Morel Yannis, Chiron Marielle, Vivier Eric |
| 764586 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
850 Dual blockade of the EP2 and EP4 PGE2 receptors with TPST-1495 is an optimal approach for drugging the prostaglandin pathway |
2021-11-01 |
10.1136/jitc-2021-sitc2021.850 |
Francica Brian, Lopez Justine, Holtz Anja, Freund Dave, Wang Dingzhi, Enstrom Amanda, Whiting Sam, Whiting Chan, Dubensky Thomas |
| 764585 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
848 Novel small molecule HPK1 inhibitor PCC-1 induces strong anti-tumor activity |
2021-11-01 |
10.1136/jitc-2021-sitc2021.848 |
Das Sanjib, Mandadi Sravan, Saini Jagmohan, Chaudhari Sachin, Deshpande Ameya, Chinnapattu Murugan, Bajpai Malini, Pangre Priyanka, Potdar Varada, Marathe Megha, Sawant Pooja, Akarte Atul, Misra Chandrasekhar, Das Subhadip, Singh Anuj, Das Avratanu, Lambade Pandurang, Tirumalasetty Chaitanya, Patole Raju, Biswas Nilanjana, Karande Vikas, Shah Heta, Behera Dayanidhi, Gowda Nagaraj, Iyer Pravin |
| 764584 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
847 Pharmacokinetics and pharmacodynamics of GS-3583 in cynomolgus monkeys |
2021-11-01 |
10.1136/jitc-2021-sitc2021.847 |
Kuhne Michelle, Chu Hamlet, Clarke Christopher, Carr Brian, Baca Manuel, Hung Magdeleine, Nagel Mark, Ambrogelly Alexandre, Rajakumaraswamy Nishanathan |
| 764583 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
843 Development and engineering of human sialidase for degradation of immunosuppressive sialoglycans to treat cancer |
2021-11-01 |
10.1136/jitc-2021-sitc2021.843 |
Peng Li, Cao Lizhi, Nerle Sujata, LeBlanc Robert, Das Abhishek, Shelke Sandip, Turner Autumn, Che Jenny, Siddiquee Zakir, Xu Hui, Xu Lihui, Gatlin Wayne, Broderick James |
| 764582 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
832 Deep learning reveals predictive sequence concepts within immune repertoires to immunotherapy |
2021-11-01 |
10.1136/jitc-2021-sitc2021.832 |
Sidhom John-William, Sidhom John-William, Sidhom John-William, Ross-Macdonald Petra, Wind-Rotolo Megan, Pardoll Andrew, Baras Alexander |
| 764581 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
831 Exact Shapley values for explaining complex machine learning based molecular tests of checkpoint inhibitors: potential utility for patients, physicians, and translational research |
2021-11-01 |
10.1136/jitc-2021-sitc2021.831 |
Roder Heinrich, Net Lelia, Roder Joanna, Campbell Thomas, McCleland Mark, Zou Wei, Srivastava Minu, Shames David, Maguire Laura, Georgantas Robert |
| 764580 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
829 Spatial arrangement and density of tumor-infiltrating lymphocytes (TILs) predicts response to immunotherapy in head and neck squamous cell carcinoma patients |
2021-11-01 |
10.1136/jitc-2021-sitc2021.829 |
Nag Reetoja, Corredor Germán, Viswanathan Vidya, Fu Pingfu, Lewis James, Wasman Jay, Teknos Theodoros, Patel Monaliben, Pan Quintin, Madabhushi Anant |
| 764579 |
JOURNAL FOR IMMUNOTHERAPY OF CANCER |
316 Leucine-rich repeats and immunoglobulin-like domains protein 1 is highly expressed on tumor-infiltrating T cells and may play a role in modulating T cell activation |
2021-11-01 |
10.1136/jitc-2021-sitc2021.316 |
Wang Li, Chan Timothy, Gilmour Cassandra, Zhang Keman, Alban Tyler, Ta Hieu, Ta Hieu |
