778738 |
MOLECULAR MEDICINE |
OTC intron 4 variations mediate pathogenic splicing patterns caused by the c.386G>A mutation in humans and spfash mice, and govern susceptibility to RNA-based therapies |
2021-12-01 |
10.1186/s10020-021-00418-9 |
Sacchetto Claudia, Peretto Laura, Baralle Francisco, Maestri Iva, Tassi Francesca, Bernardi Francesco, van de Graaf Stan F. J., Pagani Franco, Pinotti Mirko, Balestra Dario |
778737 |
MOLECULAR MEDICINE |
Syndecan-1, an indicator of endothelial glycocalyx degradation, predicts outcome of patients admitted to an ICU with COVID-19 |
2021-12-01 |
10.1186/s10020-021-00412-1 |
Zhang Dong, Li Liubing, Chen Yu, Ma Jie, Yang Yanli, Aodeng Surita, Cui Qiuju, Wen Kedi, Xiao Meng, Xie Jing, Xu Yingchun, Li Yongzhe |
778736 |
MOLECULAR MEDICINE |
Rab31-dependent regulation of transforming growth factor ß expression in breast cancer cells |
2021-12-01 |
10.1186/s10020-021-00419-8 |
Soelch Susanne, Beaufort Nathalie, Loessner Daniela, Kotzsch Matthias, Reuning Ute, Luther Thomas, Kirchner Thomas, Magdolen Viktor |
778735 |
MOLECULAR MEDICINE |
Risk surveillance and mitigation: autoantibodies as triggers and inhibitors of severe reactions to SARS-CoV-2 infection |
2021-12-01 |
10.1186/s10020-021-00422-z |
Chen Catherine, Amelia Aisah, Ashdown George W., Mueller Ivo, Coussens Anna K., Eriksson Emily M. |
778734 |
MOLECULAR MEDICINE |
Targeting CK2 mediated signaling to impair/tackle SARS-CoV-2 infection: a computational biology approach |
2021-12-01 |
10.1186/s10020-021-00424-x |
Miranda Jamilet, Bringas Ricardo, Fernandez-de-Cossio Jorge, Perera-Negrin Yasser |
778733 |
MOLECULAR MEDICINE |
Long non-coding RNA XIST: a novel oncogene in multiple cancers |
2021-12-01 |
10.1186/s10020-021-00421-0 |
Yang Jun, Qi Manlong, Fei Xiang, Wang Xia, Wang Kefeng |
778732 |
MOLECULAR MEDICINE |
Metformin alleviates the calcification of aortic valve interstitial cells through activating the PI3K/AKT pathway in an AMPK dependent way |
2021-12-01 |
10.1186/s10020-021-00416-x |
En Qiao, Zeping Huang, Yuetang Wang, Xu Wang, Wei Wang |
778731 |
MOLECULAR MEDICINE |
Microfibrillar-associated protein 5 regulates osteogenic differentiation by modulating the Wnt/β-catenin and AMPK signaling pathways |
2021-12-01 |
10.1186/s10020-021-00413-0 |
Li Haoran, Zhou Wuling, Sun Shiwei, Zhang Tianlong, Zhang Tieqi, Huang Haitian, Wang Minghai |
778730 |
MOLECULAR MEDICINE |
The effect and mechanism of Jiao-tai-wan in the treatment of diabetes mellitus with depression based on network pharmacology and experimental analysis |
2021-12-01 |
10.1186/s10020-021-00414-z |
Tang Yueheng, Su Hao, Wang Hongzhan, Lu Fuer, Nie Kexin, Wang Zhi, Huang Wenya, Dong Hui |
778729 |
MOLECULAR MEDICINE |
IL4/IL4R signaling promotes the osteolysis in metastatic bone of CRC through regulating the proliferation of osteoclast precursors |
2021-12-01 |
10.1186/s10020-021-00411-2 |
Jin Qian, Yang He, Jing Zhao, Hong-hua Wu, Ben-jing Song, Li-ting Wang, Li-juan Ye, Wei Xu, Xia Kang, Juan Wu, Wei Zheng |