Systems and methods are disclosed for increasing a nuclear spin polarization in a target compound. A parahydrogenated solution can be generated using a solvent, parahydrogen gas, and a precursor of the target compound. A polarized solution containing the hyperpolarized target compound can be generated using a polarization device and the parahydrogenated solution. The polarization device can include a polarization chamber, one or more radiofrequency (RF) coils disposed around the polarization region, a magnetic field source disposed around the polarization region, and an RF waveform generator configurable to apply a polarization transfer waveform to the one or more RF coils. The polarization chamber can include a polarization region having a volume of at least 10 milliliters (mL). The magnetic field source can be configured to provide a mean magnetic field strength of at most 200 millitesla (mT). A purified fraction can be separated from the polarized solution using a purification system.
- 출원번호 : 18988633
- 출원인 : NVISION IMAGING TECHNOLOGIES GMBH
- 특허번호 :
- IPC : G01R-033/28(2006.01);G01R-033/30(2006.01);G01R-033/31(2006.01);G01R-033/42(2006.01);G01R-033/465(2006.01);