Systems and methods are disclosed for increasing a nuclear spin polarization of a target compound. In accordance with such systems and methods, a first non-thermal equilibrium nuclear spin polarization can be imparted to at least one source atom of a source compound, the source atom having a nuclear gyromagnetic ratio of at least 12 megahertz per tesla (MHz/T). A first solution can be obtained that includes the source compound and a target compound. The at least one source atom can be present in a source concentration of at least 0.1 molar (M) in the first solution. A second non-thermal equilibrium nuclear spin polarization of at least 0.01% can be imparted to the at least one target atom of the target compound via a nuclear Overhauser effect (NOE) transfer of the first non-thermal equilibrium nuclear spin polarization to the at least one target atom.

• 출원번호 : 18764964
• 출원인 : NVISION IMAGING TECHNOLOGIES GMBH
• 특허번호 :
• IPC : G01R-033/36(2006.01);A61K-049/10(2006.01);B01D-011/04(2006.01);

A radiographic imaging apparatus of the present disclosure includes an image outputter outputting a first radiographic image included in continuous radiographic images obtained by radiographic imaging of a subject, an image brightness information extractor obtaining brightness information from the first radiographic image, a first irradiation condition calculator determining a first irradiation condition based on the brightness information, an irradiation controller controlling a radiation dose based on the first irradiation condition, a second irradiation condition calculator determining a second irradiation condition based on a second radiographic image generated based on the first irradiation condition when an imaging site of the subject is fixed, and a dose reducer reducing or maintaining the radiation dose based on the second irradiation condition.

• 출원번호 : 18762765
• 출원인 : DRTECH CORPORATION
• 특허번호 :
• IPC : A61B-006/00(2006.01)

A method of forming a pattern in a photoresist layer includes forming a photoresist layer over a substrate, and reducing moisture or oxygen absorption characteristics of the photoresist layer. The photoresist layer is selectively exposed to actinic radiation to form a latent pattern, and the latent pattern is developed by applying a developer to the selectively exposed photoresist layer to form a pattern.

• 출원번호 : 18761585
• 출원인 : Taiwan Semiconductor Manufacturing Company, Ltd.
• 특허번호 :
• IPC : H01L-021/027(2006.01);H01L-021/02(2006.01);

An endoscopic imaging system for use in a light deficient environment includes an imaging device having a tube, one or more image sensors, and a lens assembly including at least one optical elements that corresponds to the one or more image sensors. The endoscopic system includes a display for a user to visualize a scene and an image signal processing controller. The endoscopic system includes a light engine having an illumination source generating one or more pulses of electromagnetic radiation and a lumen transmitting one or more pulses of electromagnetic radiation to a distal tip of an endoscope.

• 출원번호 : 18762286
• 출원인 : Cilag GmbH International
• 특허번호 :
• IPC : G06T-007/521(2006.01);A61B-001/00(2006.01);A61B-001/04(2006.01);A61B-001/045(2006.01);A61B-001/05(2006.01);A61B-001/06(2006.01);G01J-003/02(2006.01);G01J-003/10(2006.01);G01J-003/28(2006.01);G02B-023/24(2006.01);H04N-005/265(2006.01);H04N-005/272(2006.01);H04N-013/239(2006.01);H04N-023/10(2006.01);H04N-023/13(2006.01);H04N-023/45(2006.01);H04N-023/50(2006.01);H04N-023/56(2006.01);H04N-023/74(2006.01);H04N-023/741(2006.01);H04N-023/84(2006.01);H04N-025/53(2006.01);H04N-025/533(2006.01);

A nuclear fuel assembly for a nuclear reactor core, the fuel assembly having at least one fuel element including an elongated shell defining an interior volume, a lattice structure disposed within the interior volume, at least one flow channel extending through the lattice structure, at least one lattice site disposed in the lattice structure, and at least one fuel compact disposed within a corresponding one of the at least one lattice site, a first end cap including a boss having a first cross-sectional shape, the first end cap being affixed to a first end of the shell, and a second end cap including a first bore having a second cross-sectional shape, the second end cap being affixed to a second end of the shell, wherein the first cross-sectional shape of the boss is the same as the cross-sectional shape of the bore.

• 출원번호 : 18761926
• 출원인 : Shargots, Scott J.
• 특허번호 :
• IPC : G21C-003/33(2006.01);G21C-003/322(2006.01);G21C-005/02(2006.01);G21D-005/02(2006.01);

A method of treating teeth includes applying a semisolid oral dispersion to at least one tooth. The semisolid oral dispersion includes a hydrophilic discontinuous phase comprising bleaching agent particles and a hydrophobic continuous phase comprising petrolatum. The method further includes maintaining the semisolid oral dispersion on the at least one tooth for a first period of time, and, after the first period of time, directing a light radiation toward the at least one tooth for a second period of time, the first period of time having a duration greater than 50% of a total duration of the first period of time and the second period of time.

• 출원번호 : 18760144
• 출원인 : SAGEL, Paul Albert
• 특허번호 :
• IPC : A61C-019/06(2006.01);A61K-008/21(2006.01);A61K-008/22(2006.01);A61K-008/42(2006.01);A61K-008/81(2006.01);A61K-008/92(2006.01);A61Q-011/00(2006.01);

Interstitial brachytherapy is a cancer treatment in which radioactive material is placed directly in the target tissue of the affected site using an afterloader. The accuracy of radiation placement is monitored during the cancer treatment. The location plan for the radioactive material may be adjusted during the cancer treatment based on real-time analysis of the location and dosage of radiation measured in, at and around the target tissue of the affected site.

• 출원번호 : 18760752
• 출원인 : da Conceição Moutinho, Luis Miguel
• 특허번호 :
• IPC : A61N-005/10(2006.01);A61N-005/01(2006.01);

A control apparatus includes a detection unit configured to detect switching between a plurality of radiation detection apparatuses, each of the plurality of radiation detection apparatuses being configured to capture a radiographic image through detection of radiation and including a plurality of receptor fields for performing automatic exposure control, an acquisition unit configured to acquire information regarding one of the plurality of radiation detection apparatuses to be used for image capturing in a case where switching to the one of the plurality of radiation detection apparatuses has been detected, and a selection unit configured to select one or more of the plurality of receptor fields of the one of the plurality of radiation detection apparatuses to be used for the image capturing based on the acquired information and information of a subject as an image capturing target and information of a part of the subject to be imaged.

• 출원번호 : 18761168
• 출원인 : Kawai, Masaya
• 특허번호 :
• IPC : G01T-001/17(2006.01);A61B-006/00(2006.01);G01N-023/04(2006.01);

Matrix compositions comprising structurally diverse matrix particles (1) formed from at least five different types of primary particles distinguishable from one another due to different characteristics, shape characteristics, or both, (2) that constitute 15-50% of the matrix composition by weight, (3) that comprise or more types of particle agglomerates, (4) where at least 33% of the weight concentration of the matrix particle mixture being composed of UV-protectant metal oxide particles having a minimum particle size of over 100 nm, (5) where scanning electron microscope analysis of the composition fails to identify any significant number of discrete matrix particles of having a size of 100 nm or less, and (6) the composition exhibits one or more of sun protection factor (SPF) of at least 30, a critical wavelength of at least 370 nm, UVA/UVB ratio of at least 0.333, and a UVA1 to UV ratio of at least 0.7.

• 출원번호 : 18761235
• 출원인 : Singleton, Laura C.
• 특허번호 :
• IPC : A61K-008/25(2006.01);A61K-008/06(2006.01);A61K-008/27(2006.01);A61K-008/29(2006.01);A61Q-017/04(2006.01);

The present invention relates to therapeutic immunoconjugates comprising SN-38 attached to an antibody or antigen-binding antibody fragment. The antibody may bind to Trop-2 or CEACAM5 and the immunoconjugate may be administered at a dosage of between 4 mg/kg and 16 mg/kg, preferably 4, 6, 8, 9, 10, 12, or 16 mg/kg. When administered at specified dosages and schedules, the immunoconjugate can reduce solid tumors in size, reduce or eliminate metastases and is effective to treat cancers resistant to standard therapies, such as radiation therapy, chemotherapy or immunotherapy. Surprisingly, the immunoconjugate is effective to treat cancers that are refractory to or relapsed from irinotecan.

• 출원번호 : 18759723
• 출원인 : Goldenberg, David M.
• 특허번호 :
• IPC : A61K-031/454(2006.01);A61K-031/337(2006.01);A61K-031/4184(2006.01);A61K-031/4375(2006.01);A61K-031/4745(2006.01);A61K-031/513(2006.01);A61K-031/675(2006.01);A61K-031/7068(2006.01);A61K-031/7088(2006.01);A61K-031/713(2006.01);A61K-039/00(2006.01);A61K-039/395(2006.01);A61K-041/00(2006.01);A61K-045/06(2006.01);A61K-047/68(2006.01);A61K-051/10(2006.01);A61N-005/10(2006.01);C07K-016/28(2006.01);C07K-016/30(2006.01);