• Book : 1070(p2)
• Pub. Date : 2025
• Page : pp.170066
• Keyword :

• Book : 1071()
• Pub. Date : 2025
• Page : pp.170075
• Keyword :

• Book : 1071()
• Pub. Date : 2025
• Page : pp.170078
• Keyword :

• Book : 1070(p2)
• Pub. Date : 2025
• Page : pp.170037
• Keyword :

• Book : 1070(p2)
• Pub. Date : 2025
• Page : pp.170008
• Keyword :

• Book : 1071()
• Pub. Date : 2025
• Page : pp.170088
• Keyword :

• Book : 1070(p1)
• Pub. Date : 2025
• Page : pp.170070
• Keyword :

• Book : 1070(p2)
• Pub. Date : 2025
• Page : pp.170010
• Keyword :

Abstract

BACKGROUND

Wheat is an important grain crop that has been under serious threat from Fusarium graminearum. Nup2, a member of the nuclear pore complex, plays an important role in regulating eukaryotic nuclear protein transport and participates in gene regulation. Dissecting the function of nuclear pore proteins in pathogenic fungi may provide effective targets for novel fungicides.

RESULTS

Mutants exhibited nutritional growth defects, asexual/sexual developmental abnormalities. Deficiency of FgNup2 resulted in increased resistance of Fusarium graminearum to cell wall disruptors and increased sensitivity to metal ions. Pathogenicity analyses showed that the mutant was significantly less virulent on flowering wheat ears, consistent with the observed decrease in deoxynivalenol (DON) production. Furthermore, we showed that FgNup2 interacts synergistically with FgTri6, a transcription factor of the TRI family, to regulate the expression of toxin‐producing genes, which, in turn, affects the biosynthesis of DON and related toxins.

CONCLUSION

This study revealed that FgNup2 plays important roles in the growth and development, cell wall integrity, stress response, pathogenicity, and DON synthesis of F. graminearum. © 2024 Society of Chemical Industry.

• Book : 81(1)
• Pub. Date : 2025
• Page : pp.44-54
• Keyword :

Abstract

In this work, the transfer of heat and changes in fluid pressure within a rectangular channel fairly packed with porous material have been studied numerically for various Darcy numbers and dimensionless porous layers. The model was run with the following assumptions: laminar flow, forced convection, isotropic porous material, local thermodynamic equilibrium, constant wall temperature boundary condition, and no thermal dissipation. The study covers a broad range for the dimensionless porous layer, 0 ≤ hr < 1, and the Darcy number, 10⁻⁴ < Da < 10⁻². The fully developed and developing flow over the channel is investigated in numerical study. It was observed that the inertia effect may be disregarded when Da < 10⁻⁴. The local dimensionless bulk temperature distribution, pressure drop, and velocity profiles were all shown to be impacted by the Darcy number and dimensionless porous layers, according to the numerical analysis results. The maximum heat transfer rate was attained when the ratio of the porous layer inside the channel was 0.8, and the pressure gradient was the highest. Partial packing of the channel with a porous material has two advantages: it increases the rate heat transmission rate and results in a much smaller pressure drop than a filled porous medium.

• Book : 54(1)
• Pub. Date : 2025
• Page : pp.5-20
• Keyword :