Weather is one of the important elements that greatly determines human activities, especially those related to economic factors. Therefore, understanding weather conditions using weather parameters as a reference is important for human life, so a method is needed to classify weather according to its category so that the information produced can be used for various needs. Determining weather conditions in an area will not run well without a reliable method that can analyze existing weather parameters. Therefore, in this study, the weather condition classification process was carried out using the multilayer perceptron algorithm, a type of neural network (NN) algorithm. All data analyzed were weather parameter data collected by mini weather stations placed on land. The weather parameters used were temperature, humidity, air pressure, wind speed, dew point, wind chill, daily rainfall, solar radiation, and UV index. This study was conducted in Palu city, Central Sulawesi Province, Indonesia. The classification process carried out by the multilayer perceptron algorithm was carried out on the Altair AI Studio application and produced an accuracy value of 93.87%, recall of 92.33%, and precision of 91.29%.

• Book : 37(1)
• Pub. Date : 2025
• Page : pp.540
• Keyword :

• Book : 18(1)
• Pub. Date : 2025
• Page : pp.101229
• Keyword :

• Book : 210()
• Pub. Date : 2025
• Page : pp.114708
• Keyword :

Abstract

Cross-coupling among the fundamental degrees of freedom in solids has been a long-standing problem in condensed matter physics. Despite its progress using predominantly three-dimensional materials, how the same physics plays out for two-dimensional materials is unknown. Here, we show that using ³¹P nuclear magnetic resonance (NMR), the van der Waals antiferromagnet NiPS3 undergoes a first-order magnetic phase transition due to the strong charge-spin coupling in a honeycomb lattice. Our ³¹P NMR spectrum near the Néel ordering temperature $ T_{\text{N}} = 155 $ K exhibits the coexistence of paramagnetic and antiferromagnetic phases within a finite temperature range. Furthermore, we observed a discontinuity in the order parameter at $ T_{\text{N}} $ and the complete absence of critical behavior of spin fluctuations above $ T_{\text{N}} $, decisively establishing the first-order nature of the magnetic transition. We propose that a charge stripe instability arising from a Zhang-Rice triplet ground state triggers the first-order magnetic transition.

• Book : 37(5)
• Pub. Date : 2025
• Page : pp.055801
• Keyword :

• Book : 1072()
• Pub. Date : 2025
• Page : pp.170026
• Keyword :

• Book : 681()
• Pub. Date : 2025
• Page : pp.161608
• Keyword :

Abstract

Background

We report on the characterization and introduction of a novel prognostic score for patients undergoing stereotactic body radiotherapy (SBRT) for the treatment of single and multiple pulmonary metastases (PMs) derived from head and neck cancer (HNC).

Methods

In this retrospective study, we examined selected factors associated with progression‐free survival (PFS) and overall survival (OS) among 59 patients with HNC treated with SBRT for a total of 118 PMs, between 2009 and 2023. Factors related to survival were included in the prognostic scoring system.

Results

Prognostic factors including histology, age, number of metastases, and performance status at first SBRT were weighted differently depending on the strength of correlation to PFS and OS. Total prognostic scores (HAMP) ranged from 13 to 24 points, with a cut‐off total score of ≤18 scoring points for patients in a high‐risk (HR) subcohort, and of ≥19 scoring points for patients in a low‐risk group (LR). Median PFS (23.8 vs. 5.5 months, p < 0.001) and OS (61.3 vs. 16.4 months, p < 0.001) were significantly longer in the low‐risk group compared to the high‐risk group.

Conclusion

The HAMP score might be a convenient tool to facilitate individualized treatment decisions and appropriate follow‐up. The accuracy and reliability of the score requires further evaluation in prospective studies.

• Book : 47(1)
• Pub. Date : 2025
• Page : pp.242-253
• Keyword :

Abstract

Background

Induction chemotherapy of docetaxel plus cisplatin (TP) is myelosuppressive, leading to severe neutropenia and febrile neutropenia (FN). Herein, we aimed to investigate the efficacy and safety of mecapegfilgrastim in the prevention of neutropenia in patients with locally advanced nasopharyngeal carcinoma who received the TP regimen.

Methods

A total of 30 treatment‐naive patients with locally advanced nasopharyngeal carcinoma were included in this study. Mecapegfilgrastim 6 mg was injected 24-48 h after the completion of induction chemotherapy with the TP regimen.

Results

The incidence of grade ≥3 neutropenia during the three induction chemotherapy cycles was 6.7% (95% CI, 0.8%-22.1%). In the first cycle of chemotherapy, the incidence of grade ≥3 neutropenia was 3.3% (95% CI, 0.1%-17.2%). No FN or antibiotic usage was reported. All 30 patients completed the induction chemotherapy cycles.

Conclusion

Mecapegfilgrastim effectively reduced the incidence of chemotherapy‐induced neutropenia and FN in patients with locally advanced nasopharyngeal carcinoma.

• Book : 47(1)
• Pub. Date : 2025
• Page : pp.263-268
• Keyword :

JOURNAL/nrgr/04.03/01300535-202508000-00027/figure1/v/2024-09-30T120553Z/r/image-tiff

Several promising plasma biomarker proteins, such as amyloid-β (Aβ), tau, neurofilament light chain, and glial fibrillary acidic protein, are widely used for the diagnosis of neurodegenerative diseases. However, little is known about the long-term stability of these biomarker proteins in plasma samples stored at -80°C. We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort. Plasma samples from 229 cognitively unimpaired individuals, encompassing healthy controls and those experiencing subjective cognitive decline, as well as 99 patients with cognitive impairment, comprising those with mild cognitive impairment and dementia, were acquired from the Sino Longitudinal Study on Cognitive Decline project. These samples were stored at -80°C for up to 6 years before being used in this study. Our results showed that plasma levels of Aβ42, Aβ40, neurofilament light chain, and glial fibrillary acidic protein were not significantly correlated with sample storage time. However, the level of total tau showed a negative correlation with sample storage time. Notably, in individuals without cognitive impairment, plasma levels of total protein and tau phosphorylated protein threonine 181 (p-tau181)also showed a negative correlation with sample storage time. This was not observed in individuals with cognitive impairment. Consequently, we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time. Therefore, caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases, such as Alzheimer’s disease. Furthermore, in cohort studies, it is important to consider the impact of storage time on the overall results.

• Book : 20(8)
• Pub. Date : 2025
• Page : pp.2373-2381
• Keyword :

We report on recent developments that enable megahertz hard X-ray phase contrast imaging (MHz XPCI) experiments at the Single Particles, Clusters, and Biomolecules and Serial Femtosecond Crystallography (SPB/SFX) instrument of the European XFEL facility (EuXFEL). We describe the technical implementation of the key components, including an MHz fast camera and a modular indirect X-ray microscope system based on fast scintillators coupled through a high-resolution optical microscope, which enable full-field X-ray microscopy with phase contrast of fast and irreversible phenomena. The image quality for MHz XPCI data showed significant improvement compared with a pilot demonstration of the technique using parallel beam illumination, which also allows access to up to 24 keV photon energies at the SPB/SFX instrument of the EuXFEL. With these developments, MHz XPCI was implemented as a new method offered for a broad user community (academic and industrial) and is accessible via standard user proposals. Furthermore, intra-train pulse diagnostics with a high few-micrometre spatial resolution and recording up to 128 images of consecutive pulses in a train at up to 1.1 MHz repetition rate is available upstream of the instrument. Together with the diagnostic camera upstream of the instrument and the MHz XPCI setup at the SPB/SFX instrument, simultaneous two-plane measurements for future beam studies and feedback for machine parameter tuning are now possible.

• Book : 32(1)
• Pub. Date : 2025
• Page :
• Keyword :