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  • 2025

    Nanoparticles (NPs) have revolutionized the field of skin protection and treatment by offering unique properties that enhance drug delivery, efficacy and safety. This review explores the advances in NP technology for various skin applications, including protection against ultraviolet (UV) radiation, treatment of skin diseases and enhancement of cosmetic products. NPs, such as zinc oxide and titanium dioxide, are extensively used in sunscreens for their effective UV-blocking capabilities without leaving a white residue. In medical applications, NPs improve active ingredients’ stability, penetration, and controlled release, making them ideal for treating skin conditions like psoriasis, eczema and skin cancer. The review also highlights the role of NPs in cosmetic formulations, where they enhance product texture, stability, and bioavailability of active ingredients, leading to better skin hydration and antiaging effects. Despite their benefits, the potential risks and regulatory challenges associated with NP use in skin products are discussed, emphasizing the need for comprehensive safety evaluations and adherence to regulatory standards. Future research directions include optimizing NP formulations for targeted delivery, reducing systemic absorption and improving patient compliance. This review underscores the transformative potential of NPs in dermatology and skincare, advocating for balanced development to maximize benefits while ensuring safety.


    • Book : 15(2)
    • Pub. Date : 2025
    • Page : pp.2430004
    • Keyword :
  • 2025

    Abstract

    A system combining the ventilated concrete floor (VCF) with solar air collector (SAC) in buildings has been applied in the western Sichuan Plateau for nighttime heating. However, the dynamic model coupled with uneven solar radiation of SAC-VCF is absent, thus the thermal behavior of the system is difficult to predict in practice. In this research, a coupled model is built to predict the thermal characteristics of the room with the SAC-VCF system under uneven solar radiation. The calculation model of VCF considers the uneven distribution of solar radiation on the floor surface, established by combining the resistance-capacitance (RC) network model and the number of transfer unit (NTU) model using the discrete method and validated by experimental data. A 3R2C model is utilized to model envelopes, validated by simulation results. The calculation error of surface temperature and room air temperature is within 5%. Then a case study is conducted with the validated model to predict the thermal performance of the SAC-VCF system with even and uneven solar radiation. Results indicate that under uneven solar radiation, the local surface temperature significantly increases to 35.1 °C, 9.1 °C higher than even solar radiation. Meanwhile, under uneven solar radiation, the heat transfer of supply air and surface of VCF is increased by 14% and 6%, respectively. Besides, the room air temperature is almost equal of two cases, while the operative temperature is 0.4 °C lower under uneven solar radiation. The model is beneficial to further study the influencing factors of this system.


    • Book : 147(1)
    • Pub. Date : 2025
    • Page : pp.011010
    • Keyword :
  • 2025


    • Book : 677(2)
    • Pub. Date : 2025
    • Page : pp.756-768
    • Keyword :
  • 2025

    Abstract

    In discussions on the nuclear restart policy in Japan, trust among stakeholders in nuclear power is often raised as an issue. However, the discussion has progressed without analyzing the trust demanded by the Japanese public. A questionnaire survey was conducted to analyze the level of trust that 4,700 Japanese citizens (100 from each of the 47 prefectures) have in nuclear stakeholders by breaking trust down into three elements: “Perceived Competence,” “Perceived Motivation,” and “Salient Value Similarity” (SVS), which have been reported in the literature. In the survey, nine stakeholders were targeted: the Nuclear Regulation Authority; the Ministry of Economy, Trade and Industry; the courts; the Diet; host municipalities; nuclear power operators and manufacturers; experts; research and international organizations; and the mass media. The analysis showed that the Japanese public is particularly interested in SVS with “nuclear power operators and manufacturers” among the various nuclear stakeholders. The SVS of “nuclear power operators and manufacturers” was highly correlated with that of organizations promoting nuclear power, suggesting that the public tends to perceive these organizations as sharing similar values. These results offer suggestions for actions that should be taken by each nuclear stakeholder to restore and improve trust.


    • Book : 11(1)
    • Pub. Date : 2025
    • Page : pp.012204
    • Keyword :
  • 2025


    • Book : 36()
    • Pub. Date : 2025
    • Page : pp.e20
    • Keyword :
  • 2025


    • Book : 541(1)
    • Pub. Date : 2025
    • Page : pp.128684
    • Keyword :
  • 2025

    JOURNAL/nrgr/04.03/01300535-202508000-00027/figure1/v/2024-09-30T120553Z/r/image-tiff

    Several promising plasma biomarker proteins, such as amyloid-β (Aβ), tau, neurofilament light chain, and glial fibrillary acidic protein, are widely used for the diagnosis of neurodegenerative diseases. However, little is known about the long-term stability of these biomarker proteins in plasma samples stored at -80°C. We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort. Plasma samples from 229 cognitively unimpaired individuals, encompassing healthy controls and those experiencing subjective cognitive decline, as well as 99 patients with cognitive impairment, comprising those with mild cognitive impairment and dementia, were acquired from the Sino Longitudinal Study on Cognitive Decline project. These samples were stored at -80°C for up to 6 years before being used in this study. Our results showed that plasma levels of Aβ42, Aβ40, neurofilament light chain, and glial fibrillary acidic protein were not significantly correlated with sample storage time. However, the level of total tau showed a negative correlation with sample storage time. Notably, in individuals without cognitive impairment, plasma levels of total protein and tau phosphorylated protein threonine 181 (p-tau181)also showed a negative correlation with sample storage time. This was not observed in individuals with cognitive impairment. Consequently, we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time. Therefore, caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases, such as Alzheimer’s disease. Furthermore, in cohort studies, it is important to consider the impact of storage time on the overall results.


    • Book : 20(8)
    • Pub. Date : 2025
    • Page : pp.2373-2381
    • Keyword :
  • 2025


    • Book : 215()
    • Pub. Date : 2025
    • Page : pp.111561
    • Keyword :
  • 2025

    Abstract

    Developing advanced stealth devices to cope with radar-infrared (IR) fusion detection and diverse application scenarios is increasingly demanded, which faces significant challenges due to conflicting microwave and IR cloaking mechanisms and functional integration limitations. Here, we propose a multiscale hierarchical structure design, integrating wrinkled MXene IR shielding layer and flexible Fe3O4@C/PDMS microwave absorption layer. The top wrinkled MXene layer induces the intensive diffuse reflection effect, shielding IR radiation signals while allowing microwave to pass through. Meanwhile, the permeable microwaves are assimilated into the bottom Fe3O4@C/PDMS layer via strong magneto-electric synergy. Through theoretical and experimental optimization, the assembled stealth devices realize a near-perfect stealth capability in both X-band (8-12 GHz) and long-wave infrared (8-14 µm) wavelength ranges. Specifically, it delivers a radar cross-section reduction of − 20 dB m2, a large apparent temperature modulation range (ΔT = 70 °C), and a low average IR emissivity of 0.35. Additionally, the optimal device demonstrates exceptional curved surface conformability, self-cleaning capability (contact angle ≈ 129°), and abrasion resistance (recovery time ≈ 5 s). This design strategy promotes the development of multispectral stealth technology and reinforces its applicability and durability in complex and hostile environments.


    • Book : 17(1)
    • Pub. Date : 2025
    • Page : pp.40
    • Keyword :
  • 2025


    • Book : 217()
    • Pub. Date : 2025
    • Page : pp.29-46
    • Keyword :