Abstract

Plasmonic nanoantennas provide unique opportunities for precise control of light-matter coupling in surface-enhanced infrared absorption (SEIRA) spectroscopy, but most of the resonant systems realized so far suffer from the obstacles of low sensitivity, narrow bandwidth, and asymmetric Fano resonance perturbations. Here, we demonstrated an overcoupled resonator with a high plasmon-molecule coupling coefficient (μ) (OC-Hμ resonator) by precisely controlling the radiation loss channel, the resonator-oscillator coupling channel, and the frequency detuning channel. We observed a strong dependence of the sensing performance on the coupling state, and demonstrated that OC-Hμ resonator has excellent sensing properties of ultra-sensitive (7.25% nm⁻¹), ultra-broadband (3-10 μm), and immune asymmetric Fano lineshapes. These characteristics represent a breakthrough in SEIRA technology and lay the foundation for specific recognition of biomolecules, trace detection, and protein secondary structure analysis using a single array (array size is 100 × 100 µm²). In addition, with the assistance of machine learning, mixture classification, concentration prediction and spectral reconstruction were achieved with the highest accuracy of 100%. Finally, we demonstrated the potential of OC-Hμ resonator for SARS-CoV-2 detection. These findings will promote the wider application of SEIRA technology, while providing new ideas for other enhanced spectroscopy technologies, quantum photonics and studying light-matter interactions.

• Book : 17(1)
• Pub. Date : 2025
• Page : pp.10
• Keyword :

• Book : 260()
• Pub. Date : 2025
• Page : pp.125341
• Keyword :

• Book : 211()
• Pub. Date : 2025
• Page : pp.110912
• Keyword :

• Book : 211()
• Pub. Date : 2025
• Page : pp.110903
• Keyword :

• Book : 1053()
• Pub. Date : 2025
• Page : pp.122962
• Keyword :

• Book : 1053()
• Pub. Date : 2025
• Page : pp.122951
• Keyword :

JOURNAL/nrgr/04.03/01300535-202507000-00032/figure1/v/2024-09-09T124005Z/r/image-tiff

A microgravity environment has been shown to cause ocular damage and affect visual acuity, but the underlying mechanisms remain unclear. Therefore, we established an animal model of weightlessness via tail suspension to examine the pathological changes and molecular mechanisms of retinal damage under microgravity. After 4 weeks of tail suspension, there were no notable alterations in retinal function and morphology, while after 8 weeks of tail suspension, significant reductions in retinal function were observed, and the outer nuclear layer was thinner, with abundant apoptotic cells. To investigate the mechanism underlying the degenerative changes that occurred in the outer nuclear layer of the retina, proteomics was used to analyze differentially expressed proteins in rat retinas after 8 weeks of tail suspension. The results showed that the expression levels of fibroblast growth factor 2 (also known as basic fibroblast growth factor) and glial fibrillary acidic protein, which are closely related to Müller cell activation, were significantly upregulated. In addition, Müller cell regeneration and Müller cell gliosis were observed after 4 and 8 weeks, respectively, of simulated weightlessness. These findings indicate that Müller cells play an important regulatory role in retinal outer nuclear layer degeneration during weightlessness.

• Book : 20(7)
• Pub. Date : 2025
• Page : pp.2116-2128
• Keyword :

This effects of viscous dissipation, angled magnetic field, Joule heating, and buoyancy forces on the conjugate heat and mass transport mixed convection stream of heat consuming hydro-magnetic Casson fluid from a permeable oscillating plate in a porous medium with suction/blowing in the existence of chemical reaction and radiation have been studied. The heat and mass transmission aspect are interpreted through the processes of conjugate heat and mass transport. This kind of study has not been analyzed earlier; hence the results of this study are novel. The model elucidatory coupled nonlinear PDEs are incurred and numerically tackled via the intense Galerkin finite element numerical scheme. Computational results showing disposition of the velocity, concentration, and the temperature profiles owing to the emerging parameters variation are displayed via graphic representations, whereas the skin-friction, Sherwood and Nusselt numbers are in tables. The study reveals that an expanding thermal radiation, heat dissipation, and conjugate heat transfer magnifies the temperature and velocity distributions, but heat consumption has shown contrary impact. An accentuating chemical reaction compresses the concentration and velocity distributions, but conjugate mass transfer impact witnessed an opposite trend. The rising Casson parameter and magnetic parameter slackens the fluid velocity, whereas porosity parameter displays the adverse effect. The fluid velocity is lessened by escalating phase angle but it upsurges with inclination angle of magnetic field. Further, it is acclaimed that the activity of suction slenderizes the fluid velocity, concentration, and temperature, while blowing has shown contrary nature. Comparative analysis reveals that our findings are in agreement with the one factual in the literature.

• Book : 16(1)
• Pub. Date : 2025
• Page : pp.39-61
• Keyword :

ABSTRACT: This report described the use of acoustic radiation force impulse (ARFI) elastography in the diagnosis of two cases of canine malignant peripheral nerve sheath tumors. Both patients presented with lameness in the thoracic limb and no response to previous clinical treatment or trauma history. Physical examination revealed muscular atrophy in one of the thoracic limbs, in both dogs. B-mode axillary ultrasound showed the presence of a predominantly hypoechogenic, heterogeneous, irregular, nonencapsulated nodule with adjacent reactivity, measuring approximately 20.1 mm x 15.4 mm in the first case and 18.3 mm x 10.7 mm in the second. ARFI elastography was performed, showing areas of significant stiffness, with an average shear wave velocity of 4.12 m/s (case 1) and 4.35 m/s (case 2), suggesting malignancy. In both cases, the affected limb was amputated, and the tumors sent for histopathological analysis, which were; subsequently, diagnosed as malignant tumors of the peripheral nerve sheath. The ultrasonographic methods used were essential in the diagnosis and therapeutic conduct.

• Book : 55(1)
• Pub. Date : 2025
• Page : pp.e20240042
• Keyword :

• Book : 210()
• Pub. Date : 2025
• Page : pp.110842
• Keyword :