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  • 2025


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  • 2025

    ABSTRACTBackgroundSeveral studies have explored the advantage of treatment with hyperbaric oxygen (HBO) for upper extremity lymphedema in irradiated breast cancer patients and reported controversial results. This prospective case series aimed to document the short‐ and long‐term efficacy of this therapy, focusing on the arm volume and functional assessment in breast cancer patients with a history of long‐standing lymphedema for more than 2 years.CaseSix breast cancer patients with long‐standing lymphedema were enrolled. All of them received breast surgery and dissection of axillary lymph nodes, chemotherapy, and postoperative radiotherapy. The average duration from the onset of lymphedema to HBO treatment was 9 ± 5.92 years (range 2–17). All patients were treated for 90 min in the HBO chamber with 100% oxygen at a higher pressure of two times the atmospheric pressure, five times a week for 30 sessions. We measured the circumference of both arms and calculated the arm volume before treatment (baseline), after 30 sessions of treatment, and after treatment at 3, 6, and 24 months. Functional assessment focused on the ability of the arm, shoulder, and hand using the Thai Quick‐DASH questionnaires, which were assessed by the patients at the same periods. The change of arm volume and Thai Quick‐DASH score at each time point were compared to the starting point data before HBO.ConclusionThe change of arm volume and mean Quick‐DASH score had decreased at 3, 6, and 24 months after treatment compared to the starting point before HBO, However, these changes were not statistically significant.
    • Book : 8(1)
    • Pub. Date : 2025
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  • 2025

    Hyperpolarized-13C magnetic resonance imaging (HP-13C MRI) was used to image changes in 13C-lactate signal during a visual stimulus condition in comparison to an eyes-closed control condition. Whole-brain 13C-pyruvate, 13C-lactate and 13C-bicarbonate production was imaged in healthy volunteers (N = 6, ages 24–33) for the two conditions using two separate hyperpolarized 13C-pyruvate injections. BOLD-fMRI scans were used to delineate regions of functional activation. 13C-metabolite signal was normalized by 13C-metabolite signal from the brainstem and the percentage change in 13C-metabolite signal conditions was calculated. A one-way Wilcoxon signed-rank test showed a significant increase in 13C-lactate in regions of activation when compared to the remainder of the brain ([Formula: see text]). No significant increase was observed in 13C-pyruvate signal ([Formula: see text]) or 13C-bicarbonate signal ([Formula: see text]). The results show an increase in 13C-lactate production in activated regions that is measurable with HP-13C MRI.
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  • 2025

    MR-guided radiotherapy (MRgRT) is novel treatment modality in Radiation Oncology that could allow a higher precision and tolerability of Radiation Treatments. This modality is possible due to dedicated systems consisting of a MR scanner mounted on a conventional linac and software that permit daily online treatment plan adaptation. Prostate cancer (PC) is one of the most common malignancies in RO clinical practice and currently under investigation with this new technology. The focus of this review is to describe the current state of the art and clinical results of MRgRT in the treatment of PC. The available technology are briefly described, as well as the published literature and possible future applications
    • Book : 24()
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  • 2025

    The relativistic jets of gamma-ray bursts (GRBs) might be powered by a black-hole (BH) hyperaccretion system. The inherent asymmetry in these jets generates recoil forces, inducing oscillations and positional deviations of the BH from equilibrium. In this study, we explore the influence of different initial BH mass, spin, and mass accretion rate, as well as their evolutions on the dynamical properties of BH under the effect of asymmetric jets. Our results reveal that the initial mass and accretion rate significantly impact the BH’s acceleration, velocity, and displacement, while the different initial spin plays a negligible role in shaping the overall dynamical evolution. Additionally, we calculate the gravitational wave (GW) strains associated with the asymmetric jets, finding that the resulting GW signals are too weak to be detected, even for nearby GRBs. These findings provide critical insights into the dynamical response of BHs to asymmetric jets and the associated GW radiation, advancing our understanding of BH physics in GRBs.
    • Book : 11(2)
    • Pub. Date : 2025
    • Page : pp.43-43
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  • 2025


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    • Pub. Date : 2025
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